摘要
调查血脂含量，特别是弄清中年男性高脂血症（ＨＬ）的特征及其变化规律对防治心血管病有着特殊重要的意义。为此，作者对２２３例中年男性ＨＬ患者和年龄、性别相当的３４９例健康人的体重指数（ＢＭＩ）、空腹血糖（ＦＢＳ）、血脂及ａｐｏＡⅠ、ＡⅡ、Ｂ１００、ＣⅡ、ＣⅢ及Ｅ的含量进行分析。结果显示：成都地区中年男性ＨＬ仍以血甘油三酯（ＴＧ）升高为其主要表现。ＴＧ超过血脂上限的Ⅱｂ、Ⅳ及Ⅴ型ＨＬ患者（占７５．３％）除血脂、ａｐｏＢ１００、ＣⅡ、ＣⅢ、Ｅ含量显著升高外，ＢＭＩ及ＦＢＳ也明显增加，而且ＴＧ升高的百分率显著超过ａｐｏ增加的百分率。ＨＬ年龄分布的结果还表明，４１～５０岁的患者仅占２５％左右，而５６～６０岁年龄段却高达５０％。文中还对ａｐｏ含量与血脂代谢的关系进行了讨论，认为中年男性，尤其是在５１～６０岁年龄段应特别注意控制膳食，增加体力活动，以防止和减少与心血管病密切相关的ＨＬ的发生。
It has been evidenced that cardiovascular diseases (CVD) relate with many risk factors and serum lipids play and essential role in the development of CVD. In order to further study hyperlipidemia (HL) in the middle aged males, we analysed the body mass index (BMI), fast blood sugar (FBS), serum lipids and apolipoproteins AⅠ, AⅡ, B100, CⅡ, CⅢ and E in 223 male HL patients aged 41 60 and 349 normal male subjects who matched the HL patients in age. The result showed that the increase of serum triglycerids (TG), was as might be expected, the major characteristic of the middle aged male HL patients in Chengdu District. Besides the serum lipid and apolipoprotein B100, CⅡ, CⅢ and E levels, the BMI and FBS levels in the Ⅱ b, Ⅳ and Ⅴ types of HL patients were significantly higher than those in the normal subjects. It also showed that in TG increased patients the increased percentages of serum lipids were significantly higher than those of apolipoproteins. The age distribution in HL patients revealed that only 25% of the HL patients were between 41 to 50 years old, while 50% in the 56～60 year old group. The relationship between apolipoprotein levels and serum lipid metabolism is also discussed. The results suggest that the 51～60 year old males should pay attention to diet and increase physical activities to reduce incidence of HL which is directly associated with CVD.
出处
《华西医科大学学报》
CSCD
1997年第1期10-13,共4页
Journal of West China University of Medical Sciences
基金
国家"八五"攻关资助项目
