1GuimbandR, Bertrand V, Moachonl C, et al. Network of inflammatory cytokines and correlation with disease activity in ulcerative colitis[J]. Am J Gastroenterol,1998,93(12) :2397 -2404.
2Saiki T, Uyamak M, Toyonaga A, et al. Detection of pre-and antiinflammatory cytokines in stool of patient with inflammatory bowel [J]. Scand J Gastroenterol, 1998,33 ( 67 ) :616 - 622.
4Ochsenkuhn T, Sackmann M, Goke B. Infliximab for acute, not steroid-refractory ulcerative colitis: a randomized pilot study [J]. Eur J Gastroenterol Hepatol,2004,16 ( 11 ) : 1167 - 1171.
5Sackmann M, Hanauer S, Loftus EV Jr, et al. An open-label study of the human anti-TNF monoclonal antibody adalimumab in subjects with prior loss of response or intolerance to intliximab for Crohn's disease[J]. Am J Gastroenterol, 2004,99 (10): 1984-1989.
6Paul AT, Gohil VM, Bhutani kk. Modulating TNF-alpha signaling with natural products [J]. Drug Discov Today, 2006, 11 (15-16):725-732.
二级参考文献12
1Louis E,Franchimont D,Piron A, et al. Tumour necrosis factor (TNF) gene polymorphism influences TNF alpha production in lipopolysaccharide (LPS) stimulated whole blood cell culture in healthy humans. Clin Exp Immunol, 1998,113: 401-406.
2Louis E, Franchimont D, Piron A, et al. Tumour necrosis fac tor (TNF) gene polymorphism influences TNF alpha production in lipopolysaccharide (LPS) stimulated whole blood cell culture in healthy humans. Clin Exp Immunol, 1998, 113: 401-406.
3Wilson AG, Gordon C, di Giovine FS, et al. A genetic association between systemic lupus erythematosus and tumor necrosis factor alpha. Eur J Immunol, 1994,24:191-195.
4Fong KY, Howe HS, Tin SK, et al. Polymorphism of the regulatory region of tumour necrosis factor alpha gene in patients with systemic lupus erythematosus. Ann Acad Med Singapore,1996,25:90-93.
5Fugger I, Morling N, Ryder LP, et al. Nco Ⅰ restriction fragment length polymorphism (RFLP) of the tumor necrosis factor region in four autoimmune diseases. Tissue Antigens, 1989,34:17-22.
6Wilson AG, de Vries N, Pociot F, et al. An allelic polymor phism within the human tumor necrosis factor alpha promoter region is strongly associated with HLA-A1, B8, DR3 alleles. J Exp Med,1993,177:557-560.
7Webb GC, Chaplin DD. Genetic variability at the human tumor necrosis factor loci. J Immunol, 1990, 145:1278-1285.
8Messer G, Spengler U, Jung MC, et al. Polymorphic structure of tumor necrosis factor (TNF) locus: an Ncol Ⅰ polymorphism in the first intron of the human TNF beta gene correlates with a variant amino acid in position 26 and a reduced level of TNF beta production. J Exp Med, 1991,173: 209-219.
9Sashio H,Tamura K, Ito R, et al. Polymorphisms of the TNF gene and the TNF receptor superfamily member 1B gene are as sociated with susceptibility to ulcerative colitis and Crohn's disease, respectively. Immunogenetics, 2002,53:1020-1027.
10Bouma G, Xia B, Crusius JB, et al. Distribution of four polymorphisms in the tumour necrosis factor (TNF) genes in patients with inflammatory bowel disease (IBD). Clin Exp Immunol, 1996, 103:391-396.
