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胰腺癌组织中骨桥蛋白的表达及意义 被引量:1

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摘要 采用免疫组化SP法检测骨桥蛋白(OPN)在胰腺癌组织中的表达,分析其与胰腺癌临床病理特征及预后的关系。结果显示,60例胰腺癌中OPN呈阳性表达41例(68.3%),而对照组15例中仅有4例呈阳性(26.7%),两者相比,P<0.05;COX回归模型多因素分析显示OPN表达对胰腺癌预后影响的相对危险度为3.093。认为骨桥蛋白在胰腺癌组织中的表达增强,OPN呈阳性表达的胰腺癌预后较差,OPN可作为胰腺癌预后的预测因子。
出处 《山东医药》 CAS 北大核心 2007年第24期56-56,共1页 Shandong Medical Journal
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