摘要
目的 了解2型糖尿病患者下肢血管病变（PVD）发生率，分析PVD的相关危险因素。方法对2003～2007年我院内分泌科住院治疗148例2型糖尿病患者进行回顾性分析。结果64．98％（96例／148例）患者多普勒超声检查提示下肢血管病变。年龄，病程，24h尿蛋白（UAE），血尿酸（uA），血肌酐（cR），收缩压增高比例，周围神经病变（DPN）比例，冠心病（cHD）比例在有下肢血管病变中均显著增高（p〈0．01）。Logistic回归分析结果表明，年龄，总胆固醇（TCH），DPN是PVD的独立危险因素（OR=1．087，1．353，2．201）。结论 2型糖尿病患者下肢血管病变发生率高，与年龄，血脂，血压，血糖以及糖尿病其他慢性并发症等多种因素有关。
Objective To assess the occurrence of peripheral vascular disease（PVD） in patients with type Ⅱ diabetes, to analyze its relative risk factor.Methods To retrospective analyze 148 cases of inpatients with typeⅡ diabetes in the department of endocrinology of our hospital from 2003 to 2007.Results Ultrasonic Doppler inspection showed 64.98% patients （96 cases/148 cases） had peripheral vascular disease. Logistic regression Analysis in age, course, and the changes of urinary protein（UAE）, uric acid（UA）, creatinine（CR）, systolic blood pressure in 24h ,and the significant changes of Peripheral nerves（P〈0.01）, showed that age, total cholesterol （TCH）and DPN are independent risk factors of PVD（OR=1.087,1.353,2.201）.Conclusion High incidence of peripheral vascular disease in Type Ⅱ diabetes Patients are related to age, serum lipids, blood pressure, blood sugar and other diabetes-related complications of chronic diseases.
出处
《中华临床医学杂志》
2007年第8期18-19,共2页
Chinese Journal of Clinical Practical Medicine
