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米索前列醇防治妊娠高血压综合征产后出血的疗效观察 被引量:8

Observation on effect of Misoprostol in preventing and treating postpartum hemorrhage caused by pregnancy induced hypertension
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摘要 目的:观察米索前列醇防治妊娠高血压综合征产后出血的疗效。方法:选择住院分娩妊娠高血压综合征(妊高症)患者182例,孕31~41周随机分为观察组和对照组,分别用米索前列醇配合缩宫素和单用缩宫素。结果:观察组产后出血发生率及产后出血量(经阴道或剖宫产)均低于对照组,两组比较有显著性差异(P〈0.05)。观察组用药后收缩压与舒张压稍有降低,但无显著差异(P〉0.05);血氧饱和度、心率、平均动脉压两组均无明显改变(P〉0.05)。结论:米索前列醇直肠用药配合缩宫素防治妊高症产后出血,疗效显著,且安全、方便。 Objective To explore the effect of Misoprostol in preventing and treating postpartum hemorrhage caused by pregnancy induced hypertension.Method 182 patients with pregnancy induced hypertension(pregnancy of 31~41 weeks) were randomly divided into the observation group and the control group,giving Misoprostol plus oxytocin and oxytocin alone,respectively.Results The occurrence of postpartum hemorrhage and the volume of bleeding in the observation group were lower than thtat in the control group,and with significant difference between the two groups(P〈0.05).The systolic and diastolic blood pressure declined a little after treatment in the observation group,but there was no significant difference(P〉0.05).There was no obvious change in saturation of blood oxygen,heart rates and mean arterial pressure both in the two groups(P〉0.05).Conclusion Misoprostol combined with oxytocin is effective,safe and convenient to patients with postpartum hemorrhage caused by pregnancy induced hypertension.
作者 李铁锴
出处 《吉林医学》 CAS 2007年第5期606-607,共2页 Jilin Medical Journal
关键词 米索前列醇 产后出血 妊娠高血压综合征 缩宫素. Misoprostol Postpartum hemorrhage Pregnancy induced hypertension Oxytocin
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