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MMP-9和IL-8水平与胎膜早破患者绒毛膜羊膜炎关系 被引量:4

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摘要 目的探讨胎膜早破孕妇血清中基质金属蛋白酶-9(MMP-9)和白细胞介素-8(IL-8)与绒毛膜羊膜炎的关系。方法选择45例胎膜早破患者为研究组,同期正常40例孕妇为对照组,采用酶联免疫吸附法和放射免疫法检测MMP-9和IL-8水平,同时行产后胎膜病理检查。结果胎膜早破孕妇血清中MMP-9和IL-8水平明显高于对照组,差异显著(P<0.05);血清中MMP-9和IL-8在重度和轻中度绒毛膜羊膜炎组差异显著(P<0.05)。结论母血母体中MMP-9和IL-8水平,可作为胎膜早破患者是否患有绒毛膜羊膜炎的辅助诊断指标。
作者 曹耀辉 肖建
出处 《河北医药》 CAS 2007年第10期1086-1087,共2页 Hebei Medical Journal
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  • 1Strongin AY, Collier I, Bannikov G, et al. Mechanism of cell surface activation of 72-kDatype Ⅳ collagenase. J Biol Chem, 1995,270:5331-5338.
  • 2Mayon E, Romerto R, Pacora P, et al. Evidence for the participation of interstitial collagenase ( matrix metallo-proteinase ) in premature rupture of membranes. Am Obstet Gynecol, 2000,183 : 914-920.
  • 3Mclaren J, Aylor DJ, Bell SC. necreased concentration of pro-matrix metalloprotenase 9 term fetal membranes overlying the cervix before labor: implications for em-brane emodeling and rapture. Am J Obstet Gynecol, 2000, 182: 409-416.
  • 4Kishida T, Yamada H, Furuta I, et al. Increased levels of interleukin-6 in cervical secretions and assessment of the uterine cervix by transvaglnal ultrasonog-raphy predict pretem premature of the membranes. Fetal Diagn Ther, 2003,18:98-104.
  • 5Edwin SS, Romero R, rathnasabapathy CM, et al. Prote in kinase C stimulates relecase of matrix metalloprote inase-9 and tissue inhibitor of metalloprote inase-1 by human decjdual cells. J Matern Fetal Nenoatal Med,2002, 12:231- 236.

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