摘要
目的探讨前列腺按摩液(EPS)中细胞因子白细胞介素-8(IL-8)在Ⅲ型前列腺炎[慢性非细菌性前列腺炎/慢性盆底疼痛综合征(CPPS)]诊断、分型中的意义。方法ELISA法检测37例临床诊断为Ⅲ型前列腺炎患者(其中ⅢA型17例,ⅢB型20例)EPS中IL-8浓度。分析2组EPS中IL-8浓度差异。结果ⅢA型EPS中IL-8水平(34.12±5049.622)pg/ml显著高于ⅢB型组水平(487.25±2495.001)pg/ml(P<0.01)。结论检测Ⅲ型前列腺炎患者EPS中IL-8水平可能有助于Ⅲ型前列腺炎分型诊断。
Objective To investigate the significance of IL-8 in prostatic secretions in the evaluation of chronic nonhacterial prostatitis/chronic pelvic pain syndrome （CPPS）. Methods IL-8 levels in EPS were evaluated by ELISA in 37 men： ⅢA（n-17）, Ⅲ B（n=20）, and the difference was analyzed between CPPS IIIAand CPPS ⅢB. Results IL-8 levels in EPS of men with CPPS ⅢA （34.12±5049.622）pg/ml were higher than men with Ⅲ B （487.25±2495.001）pg/ml （P〈0.01）. Conclusion IL-8 are elevated in the EPS of the men with CPPS ⅢA, and provide a novel means for the identification and characterization of CPPS. The cut-points for IL-8 to discriminate CPPS ⅢA from CPPS Ⅲ B need further investigation.
出处
《中国男科学杂志》
CAS
CSCD
2007年第8期41-43,共3页
Chinese Journal of Andrology
