摘要
目的观察杏丁注射液联合福辛普利治疗IgA肾病的临床效果。方法将56例IgA肾病患者随机分为杏丁注射液联合福辛普利组和福辛普利组,观察两组的疗效。结果4周后,联合组24h尿蛋白定量明显下降(P<0.01),血白蛋白(AIb)水平升高(P<0.01),疗效优于福辛普利组;4周后,联合组BUN有一定程度下降(P<0.01),疗效优于福辛普利组,联合组和单用福辛普利组治疗后,SCr比较,联合组明显低于福辛普利组(P<0.05)。结论杏丁注射液联合福辛普利治疗IgA肾病的患者,可以减轻尿蛋白,改善和稳定肾功能,疗效优于单用福辛普利者。
Objective To observe the clinical effect of XingDing injection combined with fosinalpril in the treatment of patients with lgA nephropathy. Methods Fifty - six cases of IgA nephropathy were randomly divided into 2 groups combinational group （XingDing injection combined with fosinalpril） and fosinalpril group（ fosinalpril only）. The results were analyzed. Results The concentration of 24 -- hour hours quantitation of urine protein in patients of combined group was significantly decreases 4 weeks afer treatment （ P 〈 0.01） ,whereas the level of blood album in increased greatly （ P 〈 0.01） four weeks after therapy. Meanwhile the level of BUN decreased obviously in combinational group than that of fosinalpril group （ P 〈 0.01 ）. The SCr in combinational group were less than that of fosinalpril group post - treatmenfly （ P 〈 0.05）. Conclusion The schedule of Xingding injection combined with fosinalpril can palliate urine protein, ameliorate and stabilize renal function of patients with lgA nephropathy, with a better therapeutic effect thau that using fosinalpril only.
出处
《中国热带医学》
CAS
2007年第10期1814-1815,1828,共3页
China Tropical Medicine
