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绵羊多胎基因BMPR-IB,BMP15的研究进展 被引量：5

Advances in multiple embryo genes of BMRP-IB and BMP15 in sheep
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摘要 绵羊多胎品种中的小尾寒羊和湖羊是我国优秀的地方绵羊品种,也是我国独特的绵羊遗传育种资源.国外主要有Brooroola羊、冰岛羊、爪洼羊、剑桥羊等多胎品种.目前,遗传育种研究者大多通过分子标记和候选基因的方法寻找影响绵羊多胎的主效基因,现就绵羊多胎基因的BMPR-IB,BMP15的研究现状进行综述. Han Sheep with small tail and Hu Sheep are the excellent sheep breeds in China with the characteristic of multiple embryos, which are the special resources for sheep genetic breeding. The sheep of multiple embryos in other countries are mainly Brooroola, Woodlands Thoka and Cambridge. At present, most methods of molecular markers and candidate genes are used to find the major genes. The present situation of research of BMRP-IB and BMP15 genes are summarized.
作者 黄顺国 额尔和花 王新燕 顾亚玲 高晓原
机构地区 皖南医学院 宁夏农林科学院 宁夏大学农学院
出处 《农业科学研究》 2007年第3期68-71,共4页 Journal of Agricultural Sciences
基金 宁夏自然科学基金项目(NZ0526)
关键词 绵羊 多胎 候选基因 sheep multiple embryos candidate genes
分类号 S813 [农业科学—畜牧学]
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参考文献14

  • 1MULSANT P;LECER F F;FABRE S.Mutation in bone morphogenetic protein receptor-IB is associated with in-creased ovulation rate in Booroola Merinoewes[J],2001(09).
  • 2王根林,毛鑫智,George H Davis,赵宗胜,张利军,曾永庆.DNA分析发现我国湖羊和小尾寒羊存在Booroola (FecB)多胎基因[J].南京农业大学学报,2003,26(1):104-106. 被引量：161
  • 3姜运良,吴常信.Booroola Merino绵羊多胎基因Fec^B的研究进展[J].中国畜牧杂志,1999,35(4):51-53. 被引量：35
  • 4储明星,桑林华,王金玉,方丽,叶素成.小尾寒羊高繁殖力候选基因BMP15和GDF9的研究[J].Acta Genetica Sinica,2005,32(1):38-45. 被引量：95
  • 5HANRAHAN P J;GREGAN S M;MULSANT P.Mutations in the genes for oocyte derived growth factors GDF9 and BMP15 are associated with both increase dovulation rate and sterility in Cambridge and Belclare sheep (Ovisaries)[J],2004(04).
  • 6DAVIS G H;MC EWAN J C;FENNESSY P F.Infertility due to bilateral ovarian hypoplasia in sheep homozygous(FecXI FecXI) for the Inverdale prolificacy gene located on the X chromosome,1992.
  • 7DAVIS G H;MC EWAN J C;FENNESSY P F.Evidence for the presence of a major gene influencing ovulation rate on the X chromosome of sheep[J],1991.
  • 8DAVIS G H;MCEWAN J C;FENNESSY P F.In fertility due to bilateral ovarian hypoplasia in sheep homozygous(FecXI FecXI) for the In verdale prolificacy gene located on the X chromosome,1992.
  • 9GALLOWAY S M;MC NATTY K P;CAMBRIDGE L M.Mutations in an oocyte derived growth differentiation factor gene (BMP15) cause increase dovulation rate in dinfertility in adosage sensitive manner[J],2000(3).
  • 10WILSON T;WU X Y;JUENGEL J L.Highly prolific Booroola sheep have a mutation in the intracellular kinase domain of bone morphogenetic protein IB receptor(ALK26) that is expressed in both oocytes and granulose cells,2001(04).

二级参考文献32

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  • 9Wilson T, Wu X Y, Juengel J L, Ross I K, Lumsden J M, Lord E A,Dodds K G,Walling G A, McEwan J C, O' Connell A R, McNatty K P, Montgomery G W. Highly prolific Booroola sheep have a mutation in the intracellular kinase domain of bone morphogenetic protein IB receptor (ALK-6) that is expressed in both oocytes and granulosa cells. Biol Reprod,2001,64(4) : 1225 ~ 1235.
  • 10Souza C J, MacDougall C, Campbell B K, McNeilly A S, Baird D'T.The Booroola (FecB) phenotype is associated with a mutation in the bone morphogenetic receptor type 1 B (BMPR1B) gene. J Endocrinol,2001,169(2) : 1 ~ 6.

共引文献323

同被引文献52

引证文献5

二级引证文献17

农业科学研究
2007年 第3期

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