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树突状细胞疫苗在晚期肾细胞癌治疗中的研究进展

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摘要 树突状细胞(DC)是目前发现强大的抗原提呈细胞(APC),能有效激发T细胞应答并诱导特异性细胞毒性T淋巴细胞(CTL)生成。肾癌是泌尿系常见的恶性肿瘤,发病率位于泌尿系肿瘤的第2位,其主要治疗方法是外科手术,化疗、放疗、激素治疗均不敏感。但是,由于肾癌是一种免疫原性很强的肿瘤,利用DC疫苗接种宿主、诱导或增强宿主防御功能、提高机体免疫系统对肿瘤的特异杀伤能力,已成为晚期肾癌免疫治疗中的研究热点。
出处 《国际泌尿系统杂志》 2007年第5期617-620,共4页 International Journal of Urology and Nephrology
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