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MMP-2、MMP-9与皮肤鳞癌相关性的研究进展 被引量:2

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摘要 基质金属蛋白酶是一个蛋白水解酶家族,可降解细胞外许多基质成分。MMP-2、MMP-9属于基质金属蛋白酶超家族成员中的明胶酶,其主要功能是分解细胞外基质,参与人体许多生理和病理过程。因其作用底物广泛,表达细胞众多以及在肿瘤侵袭和转移过程中发挥的重要作用而备受重视。本文综述了MMP-2和MMP-9的分子生物学特征以及其与皮肤鳞癌之间的关系。
出处 《徐州医学院学报》 CAS 2007年第9期627-630,共4页 Acta Academiae Medicinae Xuzhou
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