摘要
目的：探讨先天性脑ＴＯＲＣＨ感染病理改变与ＣＴ表现。材料与方法：分析７例经母子两代血清学检查证实的先天性ＴＯＲＣＨ感染新生儿、婴儿脑ＣＴ表现。其中先天性脑弓形虫病３例，先天性合胞病毒感染１例，先天性风疹病毒感染１例，先天性巨细胞病毒感染２例。结果：脑发育不良，脑室扩张或积水，室管膜下区及脑白质钙化斑，小头畸形，灰质移行障碍（如多小脑回畸形），脑裂畸形等是先天性脑ＴＯＲＣＨ感染的一组ＣＴ表现。感染越早，脑发育不良和畸形越严重，钙化出现的时间和范围与感染损害程度、范围及病程相关。婴幼儿期不明原因的基底节钙化斑提示先天性ＴＯＲＣＨ感染。结论：典型ＣＴ表现结合临床可提示先天性脑ＴＯＲＣＨ感染，血清学检查具有诊断意义。
Purpose: To study the neuropathologic changes and CT manifestations in congenital TORCH infection of the brain. Materials and methods: Analysis of 7 cases of congenital TORCH infection of the neonates and infants demonstrated by serum examination was performed. There were congenital toxoplasmosis 3 cases, congenital syncytial virus infection 1 case, congenital rubella virus infection 1 case, congenital cytomegalovirus infection 2 cases, and congenital herpes simplex virus infection 1 case. Results: Cerebral hypoplasia, ventricular dilatation or hydrocephalus, subependymal and parenchymal calcifications, microcephalic focal cortical migration anomalies, schizencephaly polymicrogyria, et al, were demonstrated by CT with congenital TORCH infection. The earlier the infection,the more severe the brain developmental anomalies. The extent and appearance of calcification in brain were related to the degree, extent and course of TORCH infection. Basal ganglia calcification of unknown cause in infant was suggestive of congenital TORCH infection. Conclusion: Typical CT manifestations together with clinical picture may suggest congenital TORCH infection,while serological test can be diagnostic
出处
《中华放射学杂志》
CAS
CSCD
北大核心
1997年第3期160-163,共4页
Chinese Journal of Radiology
关键词
病毒性脑炎
弓形体先天性
CT
新生儿
婴儿
Encephalitis, viral Toxoplasmosis, congenital Tomography,X ray computed
