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血浆uPA系统与非小细胞肺癌相关性探讨 被引量:1

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摘要 应用ELISA法检测78例非小细胞肺癌(NSCLC)患者治疗前后血浆尿激酶型纤溶酶原激活因子及其受体、抑制因子(uPA,uPAR,PAI-1)水平。结果NSCLC患者治疗前血浆uPA、uPAR和PAI-1水平均显著升高(P均<0.001),治疗后均下降。血浆uPA、uPAR、PAI-1水平与肿瘤大小、TNM分期及淋巴结转移相关;与病理类型及分化程度无关。血浆uPA、uPAR、PAI-1之间均呈直线相关。提示血浆uPA、uPAR和PAI-1可作为肿瘤标志物用于肺癌的诊断和病情观察。
出处 《山东医药》 CAS 北大核心 2007年第26期60-61,共2页 Shandong Medical Journal
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