摘要
目的观察电针、艾灸、埋线对实验性痛经大鼠T细胞亚群水平的影响。方法已烯雌酚和催产素模拟制作痛经模型,观察痛经大鼠的扭体反应情况和大鼠胸腺、脾脏的变化,检测大鼠血浆CD3、CD4、CD8的水平。结果电针、艾灸、埋线能明显减少痛经模型30 min内扭体次数,与模型组比较差异有统计学意义(P<0.01);模型组CD3、CD4与对照组比较差异有统计学意义(P<0.01),存在明显的免疫功能低下。电针、艾灸、埋线组CD3、CD4与模型组比较差异有统计学意义(P<0.01)。模型组免疫器官胸腺和脾脏发生了明显的病理变化,电针、艾灸、埋线组的胸腺和脾脏的病理变化较模型组有一定的改善。结论电针、艾灸、埋线不但有很好的止痛或缓解疼痛的作用,而且对拟原发性痛经大鼠外周血T淋巴细胞亚群和免疫器官都有影响,在一定程度上拮抗了原发性痛经出现的免疫功能低下。
Objective To investigate the influences of electroacupuncture, moxibustion and catgut embedding on T lymphocyte subgroups in experimental dysmenorrhea rats. Methods A model of dysmenorrhea was made with diethylstilbestrol and oxytocin. Body twist response and changes in the thymus gland and spleen were observed in dysmenorrhea rats. Serum CD3, CD4 and CD8 levels were measured in the rats. Results Electroacupuncture, moxibustion and catgut embedding could significantly decreased the number of body twists in dysmenorrhea rats as compared with the model group （P 〈 0.01 ）. CD3 and CD4 in the model group was significantly different from those in the normal group （ P 〈 0.01 ） ; the model group had markedly low immune function. There were significant differences in CD3 and CD4 between electroacupuncture, moxibustion or catgut embedding group and model group （P 〈 0.01 ）. The model group had obvious pathological changes in the immune organs, thymus gland and spleen. The pathological changes in the thymus gland and spleen were improved to a certain degree in the electroacupuncture, moxibustion and catgut embedding groups as compared with the model group. Conclusion Electroacupuncture, moxibustion and catgut embedding not only have a good analgesic effect but also influence peripheral blood T lymphocyte subgroups and immune organs and improve low immune function to a certain degree in primary dysmenorrhea rats.
出处
《上海针灸杂志》
2007年第9期43-45,共3页
Shanghai Journal of Acupuncture and Moxibustion
基金
广东省中医药局科研课题(1040151)
关键词
针灸
原发性痛经
免疫
Acupuncture and moxibusion
Primary dysmenorrheal
Immunity
