摘要
目的评价中药宁心宝与西药心先安结合治疗窦性心动过缓患者的临床疗效。方法将134例60岁以上各种病因所致窦性心动过缓住院患者,应用随机数字表法分为治疗组和对照组。治疗组口服宁心宝,而对照组口服舒氟美,2组均应用心先安注射液静脉输注,每天1次,连续2周,观察2组的临床症状、体表12导联心电图及24 h动态心电图变化、生活质量改善情况。结果①临床症状改善情况2组比较有显著性差异(P<0.01);②体表12导联心电图改善情况2组比较有显著性差异(P<0.01);③24 h动态心电图总心搏次数治疗组治疗后明显增加,与对照组比较亦有显著性差异(P均<0.05);④生活质量定量指标改善情况治疗组与对照组比较有显著性差异(P<0.05或0.01);⑤生活质量定性观察,治疗组在体力健康、精神健康、总体功能改善方面明显高于对照组(P均<0.01)。结论中药宁心宝与西药心先安联合治疗老年人窦性心动过缓有明显疗效。
Objective It is to investigate the effects of Ningxinbao and meglumine cyclic adenylate combined on the treatment of sinus bradycardia. Methods 134 patients of sinus bradycardia with various cause of disease witch after 60 years old were divided into two groups randomly. The treatment group was taken Ningxinbao orally. The control group was taken comfortable fluorine orally. The meglumine cyclic adenylate was used by intravenous injection in both groups, once a day, continuously for 2 weeks. And the clinical symptoms, 12 lead electrocardiogram and the 24h continuous electrocardiogram, the improvements of life quality both groups were observed. Results ①The clinical symptoms change： there was a significant difference between two groups （P〈 0.01）. ②12 lead electrocardiogram： there was a significant difference between two groups （P〈 0.01）.③24h continuous electrocardiogram： there was a significant improvement of heart rate in treatment group after therapy and significant difference between two groups （P 〈 0.05）. ④The amount of life quality： there was a significant difference in physical strength, spirit, grade of total function and the life quality between two groups after therapy （P〈 0.05 or 0.01）. ⑤The character of life quality： there was a significant improvement in physical strength, spirit, grade of total function between two groups after therapy （ P 〈 0.01 ）. Conclusion Combined Ningxinbao with meglumine cyclic adenylate in treatment of sinus bradycardi in old people has obvious curative effect.
出处
《现代中西医结合杂志》
CAS
2007年第30期4427-4428,4476,共3页
Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词
宁心宝
心先安
中西医结合疗法
窦性心动过缓
Ningxinbao
meglumine cyclic adenylate
the treatment of TCM combined with Western medicine
sinus bradycardia
