摘要
目的:研究刺五加水煎液改善睡眠的作用。方法:采用戊巴比妥钠所致小鼠睡眠的实验方法,使用酒石酸唑吡坦片为阳性对照药。结果:刺五加水煎液对戊巴比妥钠诱导的小鼠睡眠时间具有显著延长作用,刺五加水煎液高、中、低剂量与空白对照组相比均具有显著性差异(P<0.001),刺五加水煎液低剂量组与阳性对照组比较,有显著性差异(P<0.001)。结论:刺五加水煎液具有改善睡眠作用。
Objective : The present study evaluated the sleep effects of an aqueous extract of abstract Manyprickle Acanthopanax root bark. Methods : Effects on the pentobarbital sleeping time of mice. Zolpidem tartrate tablets was the positive control drug. Results : The extract (8,16,32g/kg) significantly ( P 〈 0. 001 ) prolonged pentobarbital sleeping time in mice for blank control. The extract(8g/kg) can increase sleeping time in the positive control. Conclusion: Acanthopanax can prolong the time of sleep and improve sleep.
出处
《中华中医药学刊》
CAS
2007年第10期2084-2085,共2页
Chinese Archives of Traditional Chinese Medicine
基金
黑龙江自然科学基金资助项目(D0317)
关键词
刺五加水煎液
改善睡眠
aqueous extract of abstract Manyprickle Acanthopanax root bark
improve sleep