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肺动脉高压药物治疗的新进展 被引量：7

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摘要 近年来，随着国际上对肺动脉高压诊断分类的更新和药物治疗肺动脉高压研究的进展，使得本领域的临床研究成为备受关注的热点，尤其在肺动脉高压药物治疗的观念上，已从最初的单纯降低肺动脉压力发展到根据发病机制中的重要靶点进行干预，如阻止血管内皮细胞无序增生和血管重构、诱导内皮细胞凋亡等治疗上，并在临床上取得了明显的疗效。应该说，药物治疗正在发挥越来越重要的作用。现将近年药物治疗肺动脉高压的新进展概述如下。
作者 康健 于娜
机构地区 中国医科大学附属第一医院呼吸疾病研究所
出处 《中华结核和呼吸杂志》 CAS CSCD 北大核心 2007年第9期654-656,共3页 Chinese Journal of Tuberculosis and Respiratory Diseases
关键词 肺动脉高压 药物治疗 血管内皮细胞 内皮细胞凋亡 临床研究 肺动脉压力 诊断分类 发病机制
分类号 R543.2 [医药卫生—心血管疾病]
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参考文献18

  • 1Takaoka S, Faul JL, Doyle R. Current therapies for pulmonary arterial hypertension. Semin Cardiothorac Vasc Anesth, 2007, 11:137-148.
  • 2Barst R J, Rubin LJ, Long WA, et al. A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. The Primary Pulmonary Hypertension Study Group. N Engl J Med, 1996, 334:296-302.
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二级参考文献23

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二级引证文献21

中华结核和呼吸杂志
2007年 第9期

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