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氨酚羟考酮片用于疼痛治疗的回顾性分析 被引量:28

Retrospective analysis of oxycodone and acetaminophen tablets for the treatment of pain
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摘要 目的:探讨氨酚羟考酮片(泰勒宁片)用于疼痛镇痛效果及其安全性。方法:选取口服泰勒宁片的患者100例,观察疼痛缓解程度及其不良反应。结果:泰勒宁片用于疼痛患者中度疼痛缓解显效率为81.0%,有效率为19.0%;重度疼痛患者显效率为65.5%,有效率为24.1%;总有效率为94.0%。有头晕、嗜睡、恶心、呕吐、便秘、皮肤瘙痒、皮疹、呼吸抑制等不良反应。结论:泰勒宁片用于治疗疼痛疗效确切,不良反应小。 Objective: To assess the efficacy and safety of oxycodone and acetaminophen tablets (Tylox) for the treatment of pain. Methods: 100 patients with different pain were given Tylox. Improvements in pain and adverse effects were observed. Results: Tylox in pain treatment was good. Moderate pain relief and complete relief rate were 81.0% and 19.0% respectively. Serious pain relief rate were 65.5% and 24. 1% respectively. Total relief rate was 94.0%. Only a few patients had adverse reaction, including dizziness, lethargy, nausea, vomiting, constipation, pruritus, skin eruption and respiratory depression. Conclusion: Tylox has definite effect and slight adverse reaction in pain treatment.
出处 《中国新药杂志》 CAS CSCD 北大核心 2007年第16期1308-1310,共3页 Chinese Journal of New Drugs
关键词 氨酚羟考酮片 疼痛 疗效 药物不良反应 oxycodone and acetaminophen tablets pain therapeutic effect adverse reaction
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  • 1陈战,刘晓娟,林大富,涂永久.泰勒宁片纳肛对肛肠疾病术后镇痛效果观察[J].临床军医杂志,2004,32(4):18-19. 被引量:19
  • 2BEAVER WT,MCMILLAN D.Methodological considerations in the evaluation of analgesic combinations:acetaminophen (paracetamol) and hydrocodone in postpartum pain[J].Br J Clin Pharmacol,1980,10 (Suppl):215-223.
  • 3GAMMAITONI AR,GALER BS,BULLOCH S,et al.Randomized,double-blind,placebo-controlled comparison of the analgesic efficacy of oxycodone 10mg/acetaminophen 325mg versus controlledrelease oxycodone 20mg in postsurgical pain[J].J Clin Pharmacol,2003,43 (3):296-304.
  • 4刘国辉,杨述华,张玉.氨酚羟考酮片的临床应用评价[J].中国药学杂志,2005,40(6):468-468. 被引量:14

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