摘要
为探讨甲状腺30分钟摄99mTc比与24小时摄131I率之间的定量关系，对30例甲状腺疾病患者进行了初步研究。按常现方法测定24小时摄131I率后，每个病人静脉注射5mCi99mTcO4-,30分钟后行针孔准直甲状腺显像，准直器距颈部皮肤6cm，采集100K计数，以甲状腺ROI平均计数与颈部软组织ROI平均计数之比值作为参数，与24小时摄131I率作相关分析，推导回归方程。结果：30分钟摄99mTc与24小时提131I率呈高度正相关（r=0．72，P＜O．01），回归方程Y＝2．32X＋3．39（为摄99mTc比，Y为摄131I率）；甲亢组30分钟摄99mTc比为31．2±2.8非甲亢组为9．8±1．1。因此，30分钟摄99mTc比24小时摄131I率之间存在定量关系，并有助于区分甲亢与非甲亢病人。
30 patients with thyroid diseases wer intravenously injected 5 mci 99mTcO4- after determining routinly 24 hour 131 I intake. In 30 min all had pinhole thpoid imaging to collect 100K counts, 99m Tc thyroid intake was calculated by the rate of average counts with a region of interes (ROI) over the thyroid and neck soft tissue. The result showed that the 30 min 99mTc-pertechnetate thyroid intake rate had positive correlation with 24 hour 131 I-Nal intake (r=0.72,P<0.01), the induced linea regresion formula was Y =2. 32x+3.39 (x represent 99m TcO4- thyroid intake, y131 I thyroid intake),hyperthpoidism group had significantly higher 30 min 99mTc-pertechnetate thyroid intake than that of non-hyperthyroidism group (31.2±2.8 versus 9. 8±1.1, P<0. 01). Therefore,it may be useful in differentiating hyperthyroidism from non-hyperthyroidism.
