摘要
目的观察肝动脉化疗栓塞治疗对原发性肝癌的疗效及影响因素.方法单纯化疗(A组);化疗加碘油栓塞(B组);化疗加碘油加明胶海绵栓塞(C组).结果5年内肝动脉化疗栓塞治疗中、晚期肝癌428例,386例经2个月~50个月随访.肿瘤缩小率:A组14%,B组55%,C组79%(三组间P<001).肿瘤基本消失:C组5%,A,B两组无1例消失.生存时间:1年生存率A组0%,B组10%,C组45%,其中12例患者获Ⅱ期手术切除,切除标本病理检查见肿瘤区癌细胞全部或部分凝固坏死,瘤旁癌细胞稀疏.结论影响疗效因素与肿瘤的病理类型及血供情况,门静脉主干瘘和癌栓、肝动脉插管治疗方式有关.
AIM To evaluate the effects of hepatic artery chemoembolization in the treatment of primary hepatic cancer. METHODS Hepatic arterial infusion(HAI, group A); hepatic arterial infusion and embolization with lipiodol emulsion (HAI+HAE_Ⅰ, group B) and with lipiodol_gelfoam particles (HAI+HAE Ⅰ_Gs, group C).
关键词
肝癌
原发性
药物疗法
肝动脉栓塞
Liver neoplasms/drug therapy Chemoembolization, therapeutic