摘要
目的:分析癌性贫血患者血清促红细胞生成素(Epo)的水平及其与血红蛋白(Hb)水平的关系。方法:对53例癌性贫血、71例癌症无贫血和20例正常对照的血清用ELISA法检测Epo值。结果:(1)癌性贫血组、癌症无贫血组、对照组的血清Epo分别为:(63.08±104.1)mu/ml、(12.48±9.96)mu/ml和(8.10±4.97)mu/ml。癌性贫血组与癌症无贫血组及与对照组相比较有统计学意义(分别为P<0.001和P<0.05)。癌症无贫血组与对照组无统计学意义(P>0.05)。(2)癌性贫血患者的Epo水平与Hb水平存在负相关(r=-0.693,P<0.001)。结论:癌性贫血患者的Epo值高于癌症无贫血患者和正常人,并与Hb值呈负相关。
Objective :To explore the chnical significance of serum erythropoietin(EPO) level and the relationship between EPO level and Haemoglobin (Hb) level in patients with carcinous anemia for improving the life quality in cancer patients. Methods:The serum EPO level was detected in 38 cases of carcinous anemia, 66 cases of cancer patients without anemia and 20 cases of normal controls.Results: The mean expressing level of the serum EPO in carcinous anemia group,cancer patients without anemia group and controls was (64.0± 97.0)mu/rnl, (12.6±11.4)mu/ml, (8.1±5.0)mu/ml respectively. The mean expressing level of the serum EPO in careinous anemia group was significantly higher than that in cancer patients without anemia group and control group.There was no significant difference in the mean expressing level of the serum EPO between cancer patients without anemia group and control group.A negative correlation was found between the levels of EPO and Hb in carcinous anemia patients.Conclusion:The serum EPO level in patients with carcinous anemia was responsively increased.
出处
《现代医药卫生》
2007年第22期3328-3329,共2页
Journal of Modern Medicine & Health