摘要
[目的]观察参麦注射液治疗新生儿缺氧缺血性脑病(HIE)合并心肌损害30例的临床疗效。[方法]治疗组30例在常规治疗的基础上用参注射液2 ml.-1.d-1加入10%葡萄糖溶液50 ml中静没,每日1次,疗程7～10 d。对照组33例,仅用常规治疗。[结果]治疗组的显效率53%(16/30)和总有效率80%(24/30)均显高于对照组的21%和55%(7/33和18/33)(P﹤0.01,P﹤0.05);治疗组心率、心电图、心肌酶学恢复时间比对照组显著缩短(P﹤0.01);治疗组神经系统主要症状和体征消失时间比对照组显著缩短(P﹤0.01)。[结论]参麦注射液治疗HIE合并心肌损害疗效满意。
[Objective] To investigate the clinical effects of Shenmai injection on HIE combined with myocardial damage of neonates. [ Methods] Based on the conventional therapy, 30 patients in treatment group were intravenously dripped with Shenmai injection 2ml·^-1·d^-1 which was added in 50ml 10% glucose once a day for 7-10 days. While 33 cases in the control group were treated only with conventional therapy. [ Results] The markedly effective rate （53%） and total effective rate （80%） in treatment group were all significantly higher than those in the control group （21% and 55%）（P〈 0.01 and P〈 0.05）. Compare with the control group, subjects in the treatment group had shorter recovery time of heart rate, electrocardiogram, myocardial enzyme （P 〈 0.01 ） and shorter extinction time of neurological symptoms and signs （P 〈 0.01 ）. [ Conclusions] The clinical therapeutic effects of Shenmai injection on HIE combined with myocardial injury of neonates are satisfactory.
出处
《现代预防医学》
CAS
北大核心
2007年第20期3975-3976,共2页
Modern Preventive Medicine
关键词
新生儿
缺氧缺血性脑病
心肌损害
参麦注射液
Neonate
Hypoxic ischemic encephalopathy （HIE）
Myocardial damage
Shenmai injection
