摘要
超广谱β-内酰胺酶(ESBLs)是由质粒介导,能水解青霉素、广谱头孢菌素及单环类抗生素并产生耐药。各地区ESBLs的检出率、基因分型各不相同,细菌质粒上可以同时携带≥2种的ESBL编码基因。产ESBLs菌感染为多种危险因素所致,临床治疗产ESBLs菌感染应首选碳青霉烯类抗生素。
Extended-spectrum β-lactamases（ESBLs） is mediated by plasmids, which can hydrolyze penicilin, cephalosperin with wide spectrum and helices antibiotics and then result in durg resistance. Detection rate, Genotyping of ESBLs are different in different area. bacterial plasmid can carry two or more coding genes of ESBL. So bacteria infection with ESBLs often results from many risk factors, and carbopenems antibiotics is the first choice in its clinical therapy.
出处
《医学综述》
2007年第21期1661-1663,共3页
Medical Recapitulate
