摘要
目的比较由不同临床医师制备的棉片及固定湿度棉片中所含丝裂霉素的量及临床应用效果。方法A组:3位(甲、乙、丙)临床医师按照要求分别制备20个棉片(10 mm×12 mm),每个棉片浸入浓度为0.2 mg/mL的丝裂霉素溶液中3秒,于浸入之前后测量每1个棉片的干重和湿重。B组:由另3位(甲、乙、丙)临床医师按照要求分别制备的20个棉片(10mm×12 mm),用注射器注入0.5 mL浓度为0.2 mg/mL的丝裂霉素溶液(称固定湿度棉片),于注入之前测量每个棉片的干重;并观察应用B组固定湿度棉片在36例(70眼)青光眼滤过术者中的临床效果。结果A组棉片中所含丝裂霉素的平均量为(136.8±22.5)μg,不同医师间差异有统计学意义(P<0.05);B组棉片中所含丝裂霉素量为100μg。结论固定湿度棉片携载丝裂霉素的方法可重复性较好,用量较易控制,手术中应用并发症少、降眼压效果好,取得良好的效果。
Objective To estimate the quantity of mitomycin C contained in the sponges prepared by different doctors and clinical application.Methods A group：Each of the three doctors prepared 20 sponges（10mm×12mm） and immersed in the sodium of 0.2 mg/ml mitomycin C for 3 sec,the quantity of this drug in each specimen was calculated by the difference between wet and dry weights.B group：Each of the three doctors prepared 20 sponges（10 mm×12 mm） and using syringe to add dose 0.2 mg/ml mitomycin C sodium 0.5 ml（called fixed moisture sponges） and calculated each sponge＇s dry weights.To observe clinical efficacy in treatment of patients with glaucoma filtration surgery combined mitomycin C and fixed moisture sponges. Results A group： The mean quantity of mitomycin C contained in each sponge was 136.8±22.5μg,and the difference between doctors was statistically significant（P〈0.05）.B group： The quantity of mitomycin C contained in each sponge was 100 μg. Conclusions The method of using fixed moisture sponges has greater reproducibility.Intraocular pressure and postoperative complications have been lowered.
出处
《眼外伤职业眼病杂志》
北大核心
2007年第10期782-784,共3页
Journal of Injuries and Occupational Diseases of the Eye with Ophthalmic Surgeries
