摘要
对测胰岛素敏感性的小剂量短时胰岛素耐量试验（ＩＴＴ）进行改进，用毛细血管血糖代替加热手臂使静脉血动脉化的方法，测注射胰岛素０．０５Ｕ／ｋｇ后３、６、９、１２、１５、１８分钟血糖降低的斜率，即胰岛素敏感性指数（ＫＩＴＴ值）。结果：毛细血管血糖与动脉化的静脉血血糖十分接近；两法ＫＩＴＴ也基本相同。本法测得ＫＩＴＴ，２５～３４岁正常组为３．５５±０．８９，２１～６３岁正常组为３．２９±０．８３，单纯性肥胖为２．３６±０．８９，ＮＩＤＤＭ组为１．１５±０．４９。本法重复性好、灵敏度高，较其它计算方法可靠；是一种短时、安全、可靠、方便，对患者痛苦少的测量胰岛素敏感性的方法。
The short insulin tolerance test (ITT) for determination of insulin sensitivity was improved by using capillary blood glucose instead of arterialized venous blood glucose. The profile of capillary blood glucose 3,6,9,12,15 and 18 minutes after injection of insulin (0.05U/kg) was assessed and K ITT counted. The results showed that the capillary blood glucose value was very close to the arterialized venous blood glucose value and there was no difference of K ITT between these two kinds of blood. K ITT from normal group I (25～34 yrs),normal group II (21～63 yrs), simple obesity group and NIDDM group were 3.55±0.89, 3.29±0.83, 2.36±0.89 and 1.15±0.49 respectively. Being sensitive and able to give reproducible results, the improved method is a short, safe, reliable and convenient method and can be used even in patients from out patient department.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
1997年第2期77-80,共4页
Chinese Journal of Endocrinology and Metabolism
关键词
毛细血管法
胰岛素敏感性
糖尿病
血糖测定
Capillary blood glucose Insulin sensitivity Insulin tolerance test
