摘要
目的：研究肝硬化患者腺垂体分泌细胞的储备功能。方法：用放免法测定10例男性肝硬化患者行药物腺垂体兴奋试验前后的血清PRL、GH、FSH和LH水平。结果：兴奋腺垂体前与健康对照组比较患者血清GH增高（P＜0．05）、FSH降低（P＜0．05）、LH（P＞0．05）和PRL（P＞0．05）与健康对照组比较差异无显著性，兴奋后垂体激素均值明显低于健康对照组（P值分别为，P＜0．01，P＜0．05，P＜0．05和P＜0．05），GH高峰值出现时间延迟．结论：肝硬化患者腺垂体储备功能低下．
Objective: To study the reserve function of adenohypophyseal secretory cells in patients with hepatocirrhosis. Methods: Adenohypophyseal excitatory test was made by drugs, and before and after the excitatory test the serum levels of pituitary hormones PRL,GH, FSH and LH were determined by radioimmunoassay in 10 male patients with hepatocirrhosis. Results: Be fore excitement the GH serum level was higher and the FSH serum level was lower in patients with cirrhosis than that of healthy control subjects (P<0. 05),and there were no significant differenccs of LH and PRL serum levels between patients with cirrhosis and healthy subjects(P>0. 05). After excitement all of the these hormone levels got lower and the peak level of GH was delayed in paticnts with cirrhosis compared with healthy subjects. Conclusion: Reserve function of adenohypophysis was decreased in patients with hepatocirrhosis.
出处
《广东医学院学报》
1997年第1期31-33,共3页
Journal of Guangdong Medical College
关键词
肝硬化
腺垂体
垂体激素
储备功能
hepatocirrhosis
adenohypophysis
pituitary hormone
pituitary function test
