摘要
目的:阴茎包皮系神经末梢最敏感部位之一,观察纳米银医用抗菌敷料用于包皮手术后创面的止痛防粘连效果,并与普通凡士林油纱相比较。方法:选择解放军总医院小儿外科2006-01/08收治住院手术的包茎、包皮过长、尿道下裂患儿220例,随机分为纳米银敷料组和对照组各110例。纳米银敷料组患儿术后创面覆盖以无菌生理盐水打湿后的纳米银医用抗菌敷料,对照组使用普通凡士林油纱包扎伤口,术后第3,5,7天换药。比较两组患儿术后第1,3,5,7天的疼痛感受及创面愈合情况。结果:220例患儿均进入结果分析。纳米银敷料组术后第1,3,5天疼痛较对照组轻(P<0.01);且纳米银敷料比普通油纱更容易从创面分离,换药所需时间短,换药过程不会引起创面渗血和患儿疼痛;术后第5天纳米银敷料组创面面积小于对照组(P=0.041);两组均未发现材料宿主反应。结论:纳米银医用抗菌敷料用于包皮的换药具有明确的防粘连、促进创面愈合、止痛的作用,其效果优于普通凡士林油纱。
AIM： Preputium penis is one of the most sensitive parts for nerve ending. This study is designed to observe the effect of nanometer silver antiseptic dressing on releasing pain and preventing adhesion of wound surface after circumcision, and compare with the result of common Vaseline. METHODS： A total of 220 children inpatients suffering from phimosis, redundant prepuce and hypospadias, ware enrolled from Department of Pediatric Surgery in General Hospital of Chinese PLA from January to August in 2006, and were distributed randomly to experiment group and contrast group （n =110）. After operation, the nanometer silver antiseptic dressing, which was wet by stroke-physiological saline solution, and common Vaseline gauze, were used respectively to the experiment group and contrast group. The dressings ware changed on the 3^rd, 5^th and 7^th days postoperatively. And the pain and wound healing were contrasted between the two groups on the 1^st, 3^rd, 5^lh and 7^th days. RESULTS： All of 220 children ware involved in the result analysis. Compared with contrast group, pain released significantly in the experiment group on the 1^sl, 3^rd and 5^th days postoperatively （P 〈 0.01）. It was easier for the dressing of nanometer silver to be removed from the wound surface than the common Vaseline, and dressing exchange required a shorter period and less blood oozing. On the 5^th day, the wound area of experiment group was found to be smaller than that of contrast group （P =0.041）. There was a material-host response in neither group. CONCLUSION： Nanometer silver antiseptic dressing is superior to common Vaseline gauze to prevent adhesion, stimulate the healing of wound and release pain.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2007年第40期8181-8183,共3页
Journal of Clinical Rehabilitative Tissue Engineering Research
