摘要
目的:探讨伽玛刀对垂体腺瘤的疗效。方法:56例垂体瘤患者实施立体定向伽玛刀治疗,肿瘤直径4~34.2mm(平均15.6mm),肿瘤照射野覆盖平均为67%,瘤周边剂量平均为24Gy。结果:51例随访3~21个月(平均11个月),临床症状改善36例(70.6%),激素水平恢复正常或下降19/25例(76%),肿瘤缩小25/47例(53%),仅3例肿瘤增大。结论:认为伽玛刀手术简便、安全,是治疗垂体腺瘤(尤其是微小功能性腺瘤)的又一有效方法。
Objective: To explore the therapeutic efficacy of Gamma knife on pituitary adenomas. Methods: 56 cases of pituitary adenomas were treated with stereotaotic Gamma knife. All tumors with the diameter of 4 34. 2mm (mean 15 6mm) were averagely enclosed with the 67% isodose shells of the radiosurgical fields with a radiosurgical“boost” of 24Gy to the margins. Results: 51 cases were followed up for 3 to 21 months with median in 11 months. The clinical symptoms and signs were improved in 36 cases (70 6%). The hormone levels became normal or decreased in 19 out of 25 cases (76%), and the tumor size shrank in 25 out of 47 cases (53%). Only 3 cases grew larger. Conclusion: Gamma knife operation was simple and safe, and has become one of the effective methods in the treatment of pituitary adenomas, especially for micro functional ones.
出处
《中华神经外科杂志》
CSCD
北大核心
1997年第2期76-78,共3页
Chinese Journal of Neurosurgery
关键词
垂体肿瘤
伽玛刀
Pituitary adenomas Gamma knife Treatment