摘要
本研究在三层同心球模型上利用有限差分法求解开颅手术后的脑电正问题,通过与开颅术前脑电正问题的解进行比较,研究颅骨上的洞对头皮电位分布的影响。仿真试验表明,颅骨开洞对头皮电位分布的影响程度取决于偶极子源的位置和方向:径向偶极子源位于洞正下方时,洞对头皮电位分布的影响最大;而切向偶极子源靠近洞边缘时的影响最大。
In this paper, a finite difference method (FDM) was implemented to solve the electroencephalogram (EEG) forward problem for three-concentric-sphere model with skull burr hole. The influence on the EEG forward solutions of the holes in the skull was studied by comparing the forward potential distributions with and without a hole, Computer simulations suggested that the influence of a hole on the EEG recordings strongly depended on the dipole location and orientation. For a radial dipole, the strongest effect on the EEG occurred when it was located below the center of the hole, while for a tangential dipole the strongest effect occurred when it was located below the border of the hole.
出处
《中国生物医学工程学报》
CAS
CSCD
北大核心
2007年第5期708-712,共5页
Chinese Journal of Biomedical Engineering
基金
国家自然科学基金资助项目(NSFC-50577055)
美国国家卫生研究所(EB00178)
美国国家科学基金会(BES-0411898)。