摘要
目的探讨癌胚抗原(CEA)检测在乳腺癌诊断和判断预后中的作用。方法应用免疫组化方法检测64例乳腺癌、37例正常及良性病变中癌胚抗原的表达。结果乳腺癌中癌胚抗原的阳性率(68.8%)明显高于正常对照组(16.2%),有显著性差异(P<0.05)。乳腺癌有淋巴结转移的癌胚抗原的阳性率(81.3%),略高于乳腺癌没有淋巴结转移的癌胚抗原的阳性率(56.3%),无显著性差异。结论癌胚抗原的检测有助于乳腺癌的诊断,癌胚抗原可能是判断乳腺癌预后的重要指标。
Objective To investigate the diagnostic value of determination of serum carcinoembryonic antigen （CEA） level for breast cancer. Methods The expression of carcinoembryonic antigen was observed by immunohistochemical assay in 64 breast cancer and 37 benign breast lesions. Results The expression of carcinoembryonic antigen in breast cancer was higher than that of benign breast lesions, and there was significant differences（P 〈 0.01 ）. The expression of carcinoembryonic antigen in breast cancer patients with regional lymph node metastasis was little higher than that without regional lymph node metastasis, and there wash＇ t a significant differences（P 〈 0.05）. Conclusion Carcinoembryonic antigen has clinical value that can be used to help the diagnosis of breast cancer. Carcinoembryonic antigen is an important factor to determine the prognosis of breast cancer.
出处
《实用药物与临床》
CAS
2007年第5期279-280,共2页
Practical Pharmacy and Clinical Remedies
关键词
癌胚抗原
乳腺癌
临床意义
Carcinoembryonic antigen
Breast cancer
