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卡泊芬净在中性粒细胞缺乏伴持续发热患者经验性抗真菌治疗中的疗效观察 被引量:1

Clinical evaluation of caspofungin as empirical antifungal therapy in patients with persistent fever and agranulocytosis
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摘要 卡泊芬净(caspofungin acetate,亦称MK20991,L2743872)是第一个批准用于临床的棘白菌素。此类药物毒性低,对大多数临床分离的念珠菌属和曲霉属均有快速杀菌作用。在血液科恶性肿瘤接受化疗或进行造血干细胞移植、再生障碍性贫血等发生中性粒细胞缺乏的患者中,侵袭性真菌感染是其重要的死亡原因。本研究报道5例中性粒细胞缺乏患者经验性应用卡泊芬净的疗效与不良反应。
出处 《中国感染与化疗杂志》 CAS 2007年第5期352-353,共2页 Chinese Journal of Infection and Chemotherapy
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