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拉帕替尼(lapatinb) 被引量:7

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作者 刘斯婕 胡春
机构地区 沈阳药科大学
出处 《中国药物化学杂志》 CAS CSCD 2007年第5期333-333,共1页 Chinese Journal of Medicinal Chemistry
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参考文献5

  • 1U S FDA.FDA approves Tykerb for advanced breast cancer patients[EB/OL].[2007-06-25].http://www.fda.gov/bbs/topics/NEWS/2007/NEW01586.html.
  • 2RUBIN S.Lapatinib compounds for the treatment of breast cancer that has metastasized to the brain; WO,2006/066267[P].2006-06-22.
  • 3MAUNG K,O'SHAUGHNESSY J A.Inhibition of ErbB1 and ErbB2 by lapatinib ditosylate,a dual kinase inhibitor:Promising activity in pretreated advanced breast cancer[J].Clin Breast Cancer,2004,6:398-400.
  • 4ASTSATUROV I,COHEN R B,HARARI P.Targeting epidermal growth factor receptor signaling in the treatment of head and neck cancer[J].Expert Rev Anticancer Ther,2006,6(9):1179-1193.
  • 5Glaxo Smith Kline.Safety data sheet[EB/OL].[2007-06 -25].http://www.msds-gsk.com/12712608.pdf.

同被引文献39

  • 1吕峰,刘玉婷,邹竞,张大德,姚祖光.固体光气在有机合成中的应用[J].信息记录材料,2004,5(3):21-25. 被引量:15
  • 2徐兵河.乳腺癌分子靶向治疗的研究进展[J].中国处方药,2006,5(8):38-41. 被引量:3
  • 3Petrov KG, Zhang YM, Carter M, et al. Optimization and SAR for dual ErbB-1/ErbB-2 tyrosine kinase inhibition in the 6-furanylquinazoline series [J]. Bioorg Med Chem Lett, 2006, 16(17): 4686-4691.
  • 4Soghra K, Didier P, Alexander M, et al. Design, synthesis and evaluation of 2,4-diaminoquinazolines as inhibitors of trypanosomal and leishmanial dihydrofolate reductase [J]. Bioorg Med Chem, 2005, 13 (7) : 2637-2649.
  • 5Balcom D, Furst A. Reductions with hydrazine hydrate catalyzed by Raney nickel. I. Aromatic nitro compounds to amines [J]. J Am Chem Soc, 1953, 75(17): 4334.
  • 6Wissner A, Fraser HL, Ingalls CL, et al. Dual irreversible kinase inhibitors: quinazoline-based inhibitors incoiporating two independent reactive centers with each targeting different cysteine residues in the kinase domains of EGFR and VEGFR-2 [J]. Bioorg Med Chem, 2007, 15(11): 3635-3648.
  • 7Fischer RW, Misun M. Large-scale synthesis of a pyrrolo[2,3-d]pyrimidine via Dakin-West reaction and Dimroth rearrangement [J]. Org Proc Res Dev, 2001, 5 (6) : 581-586.
  • 8Mcclure MS, Osterhout MH, Roschangar F, et al. Quinazoline ditosylate salt compounds: WO, 2002002552[P]. 2002-01-10.
  • 9Abdel-Magid AF, Carson KG, Harris BD, et al. Reductive amination of aldehydes and ketones with sodium triacetoxyborohydride studies on direct and indirect reductive amination procedures [J]. J Org Chem, 1996, 61 (11) : 3849-3862.
  • 10Byung HH, Dae HS, Sung YC. Graphite catalyzed reduction of aromatic and aliphatic nitro compounds with hydrazine hydrate [J]. Tetrahedron Lett, 1985, 26 (50): 6233-6234.

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