摘要
造成家兔门静脉及其属支狭窄复制门脉高压症模型。术后二月出现腹壁静脉怒张;门静脉狭窄远心端血管明显扩张,瘀血;脾脏肿大,脾窦扩张、瘀血、炎性细胞浸润;胃贲门及食管粘膜下血管明显扩张,直径为226.89±86.27μm(X±SD),与对照组相比有显著性差异。从贲门浆膜下静脉快速注入TH胶后,实验组动物贲门及食管粘膜下血管内均有TH胶栓塞,TH胶栓塞血管的最小直径为26μm,能有效防治粘膜下扩张静脉出血。
An experimental model of portal hypertension was made by coarctating the portal vein and it's branch in rabbits. Two months after the operation, vari- cosity of the abdominal wall, hemangiectasis and congestion of the distal end of coarctating portal vein and splenomegaly were observed. Sections of the spleen showed congestion and inflammatory cells inflltration. The calib- bers of the submucous vessels of the esophagus and the cardia of the stomach in the experimental group increased more significantly than that of the vessels in the control group (p<0.001). Colloidal solution of TH was injectea ra- pidly into the subserous vein of the cardia of the stomac found in all the sub- moucus vessels of both the esophagus and the cardia of the stomach. The mi nimal caliber of the embolismic vessels by colloidal solution of TH was 26 μm. The results suggest the injection of TH can prevent effectively the he- morrhage of ectatic veins in portal hypertension and isvaluable in studying por- tal hypertension.
出处
《贵阳医学院学报》
CAS
1990年第3期189-191,共3页
Journal of Guiyang Medical College
关键词
门脉高压症
食管静脉曲张
rabbit
portal hypertension
esophageal varices
therapeutic embolization
