摘要
目的调查2型糖尿病(T2DM)患者心率变异性(HRV)及其影响因素。方法调查了364例T2DM患者的年龄、糖尿病病程、冠心病病程、高血压病程、脑血管病病程、血脂、血糖等和24hHRV频域及时域指标。结果与对照组比较,T2DM患者HRV各项指标明显降低。多因素分析提示,DM病程、脉压、高血压病程、年龄、收缩压、BUN、餐后血糖是影响HRV的主要因素。结论随着影响因素增多,T2DM,患者HRV降低越来越显著;影响因素依次是DM病程、脉压、高血压病程、年龄等。
Objective To analyze the heart rate variability （HRV） and its risk factors in type 2 diabetes patients. Method 364 patients with type 2 diabetes were recruited. The baseline data included age, dura- tion of diabetes, coronary artery disease and cerebral vessel disease, SBP, DBP, pulse pressure, BMI, waist to hip ratio, TC, TG, HDL, LDL, BUN, sCr, serum fasting glucose, postprandial glucose, HbAlc, serum fasting insulin, postprandial insulin, urinary albumin excretion rate, and Ho]ter ECG containing frequency and time threshold of heart rate variability. Result 364 diabetic patients （ 195 males, 169 females; mean age of 60 -＋ 11 years） and 136 control subjects without diabetes （81 males, 55 females; mean age of 59 ＋9 years） were en- rolled. The sex and age between the two groups were matched. Frequency and time threshold of HRV in diabetic patients were significantly decreased when compared with the control subjects （P 〈 0.01 ）. Multiple regression a- nalysis suggested that the duration of diabetes and hypertension, pulse pressure, age, SBP, BUN, and postpran- dial glucose level were risk factors for heart rate variability. Conclusions HRV is decreased in diabetic pa- tients, and become more diminished with the risk factors increasing.
出处
《中国糖尿病杂志》
CAS
CSCD
北大核心
2007年第10期601-603,共3页
Chinese Journal of Diabetes
关键词
糖尿病
2型
心率变异性
冠心病
高血压
Diabetes, type 2
Heart rate variability
Coronary artery disease
Hypertension
