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Eag1钾通道在胃癌中的异常表达及意义 被引量:1

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摘要 近年来,钾通道与癌的相关性研究受到广泛重视。Eag1钾通道(etheràgo-go,Kv10.1)为延迟整流电压门控钾通道,已被证实具致癌性,可作为潜在的癌症诊断和治疗工具。
出处 《中华消化杂志》 CAS CSCD 北大核心 2007年第10期695-696,共2页 Chinese Journal of Digestion
基金 湖北省卫生厅科研基金指导性资助项目(JX3C44)
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参考文献5

  • 1Felipe A, Vicente R, Villalonga N, et al. Potassium channels: new targets in cancer therapy. Cancer Detect Prey, 2006, 30: 375-385.
  • 2Pardo LA, del Camino D, Sanchez A, et al. Oncogenic potential of EAG K+ channels. EMBO J, 1999, 18:5540-5547.
  • 3Hemmerlein B, Weseloh RM, Mello de Queiroz F, et al. Over-expression of Eagl potassium channels in clinical tumours. Mol Cancer, 2006,5:41.
  • 4Garcia Ferreiro RE, Kerschensteiner D, Major F, et al. Mechanism of block of hEagl K+channels by imipramine and astemizole. J GenPhysiol, 2004,124:301-317.
  • 5Gavrilova-Ruch O, Schonherr K, Gessner G, et al. Effects of imipramine on ion channels and proliferation of IGR1 melanoma cells. J Membr Biol, 2002, 188:137-149.

同被引文献9

  • 1丁祥武,罗和生,严娟娟,安萍,吕鹏.EAG1钾通道在结直肠癌组织中的表达[J].中华病理学杂志,2007,36(6):410-411. 被引量:1
  • 2Ivan Restrepo-Angulo,Carmen Sanchez-Torres,Javier Camacho.Human EAG1 Potassium Channels in the Epithelial-to-Mesenchymal Transition in Lung Cancer Cells. Anticancer Research . 2011
  • 3Agarwal Jasmin R,Griesinger Frank,Stühmer Walter,Pardo Luis A.The potassium channel Ether à go-go is a novel prognostic factor with functional relevance in acute myeloid leukemia. Molecular cancer . 2010
  • 4Subhash C Chauhan,Ajay P Singh,Fernanda Ruiz,Sonny L Johansson,Maneesh Jain,Lynette M Smith,Nicolas Moniaux,Surinder K Batra.Aberrant expression of MUC4 in ovarian carcinoma: diagnostic significance alone and in combination with MUC1 and MUC16 (CA125). Modern Pathology . 2006
  • 5Viren Asher,Raheela Khan,Averil Warren,Robert Shaw,Gerhard V Schalkwyk,Anish Bali,Heidi M Sowter.The Eag potassium channel as a new prognostic marker in ovarian cancer. Diagnostic Pathology . 2010
  • 6Cherubini A,Taddei GL,Crociani O,et al.HERG potassium channels are more frequently expressed in human endometrial cancer as compared to non-cancerous endometrium. British Journal of Cancer . 2000
  • 7林爽,李力,易萍,郑秀惠,郭建新,韩健.宫颈癌中Eag1钾离子通道的表达以及缺氧对其的调控作用[J].重庆医学,2010,39(8):899-901. 被引量:6
  • 8金雄,丁祥武,李建军,李峥,闫泽强,王道蓉.hERG1钾通道在食管鳞癌中的表达及其意义[J].武汉大学学报(医学版),2010,31(3):304-308. 被引量:2
  • 9光君,甘璐,周勇.HERG在鳞状细胞癌中的表达[J].现代生物医学进展,2010,10(12):2336-2338. 被引量:1

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