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糖代谢紊乱对危重病人预后的影响

Glycometabolism disorders affects the prognosis of critically ill patients
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摘要 目的探讨危重病人的糖代谢紊乱与病情严重程度、预后的关系。方法应用APACHEⅢ评分系统对206例危重患者的危重程度进行评估,并观察患者病死率。结果糖尿病组、应激性高血糖组的APACHEⅢ评分均明显高于血糖正常组(P<0.01);ICU住院时间、呼吸机使用时间均较血糖正常组明显延长(P<0.01);肾功能受损害程度、发热情况均较血糖正常组严重(P<0.01)。而三组患者的TBil值和每日摄取食物的热卡差异均无显著性(P>0.05)。糖尿病组、应激性高血糖组的病死率均明显高于血糖正常组(P<0.01)。以应激性高血糖组最高(45.57%),血糖正常组最低(18.28%)。结论糖代谢紊乱可加重病情,存在糖代谢紊乱的危重患者病死率明显增高,是影响危重患者预后的危险因子之一。 Objective To evaluate the association between glycometabolism disturbance and disease severity and prognosis in critically ill patients Methods The APACHE Ⅲ prognostic system was used to evaluate the severity of 206 critically ill patients and their mortality was observed. Results In diabetic group and stress hyperglycemia group, the APACHE Ⅲ scores were all higher, compared with normal blood glucose group, there was statistical significant difference ( P 〈0.01); the in- ICU time, using respirator time were also longer, there were statistically significant differences( P 〈0.01); the kidney function injured degree and fever condition were also worse ( P 〈0.01). The comparison among these three groups indicated that TBil value and the calorie in daily food intake were almost the same, there were no statistically significant differences ( P〉0.05). Compared to the normal blood group, the mortality in the diabetic group and the stress hyperglycemia group were higher, there were statistically significant differences ( P 〈0.01), the highest mortality occurred in the stress hyperglycemia group (45.57%), the lowest occurred in the normal blood glucose group (18.28%). ease condition, the mortality increased significantly in critically ill factors in affecting the prognosis of critically ill patients. Conclusion Glycometabolism may worsen the dispatients with glycometabolism. It is one of the risk factors in affecting the prognosis of critically ill patients.
出处 《右江民族医学院学报》 2007年第6期896-898,共3页 Journal of Youjiang Medical University for Nationalities
关键词 危重病 重症监护 葡萄糖代谢障碍 高血糖 critical illness intensive care glycometabolism disorder hyperglycemia
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参考文献10

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