摘要
近红外脑功能成像技术(fNIRI)是近年来发展起来的新技术,与心理学研究常用的事件相关脑电位检测技术(ERP)相比,能提供电生理信号之外的与脑功能活动相关的血液动力学信息。设计了非随意注意的经典范式,对同一组被试者分别使用近红外脑功能成像技术和事件相关脑电位检测技术检测其在实验过程中脑活动变化,然后对两种技术检测的结果进行处理和比较分析。结果发现近红外脑功能成像技术测出的非随意注意源定位在前额叶,与其相关P3a脑电皮层分布一致,甚至近红外脑功能成像技术测出的源定位范围可以缩小到Brodmann46区;血液激活先于P3a并在P3a完成后显著增强的现象支持深入研究脑机理的可能性。因此,近红外脑功能成像技术可有效地应用于脑的高级功能研究。
Compared with event-related potential （ERP）, which is widely used in psychological research, functional near-infrared imaging （fNIRI） is a new technique, and can supply hemodynamic information related with brain activity, excepting for electrophysiological signals. We conducted a series of experiments with the classic paradigm of ocular nonselective attention, monitored responses if brain with fNIRI and ERP respectively, and then analyzed the data, The results showed us that ocular nonselective attention companied activation was on the prefrontal lobe, which had the same results as its related P3a in ERP. In fact, the fNIRI results demonstrated a smaller area of the source than ERP, which was at the middle part of Brodmann 46, and the phenomenon that the hemodynamic activation occurred before P3a and strengthened just after P3a, supported the possibility of further study in brain mechanism. Therefore, fNIRI is a potential technique in advanced function research of brain.
出处
《光学学报》
EI
CAS
CSCD
北大核心
2007年第3期531-535,共5页
Acta Optica Sinica
基金
国家自然科学基金(30070261
60478016)资助课题。
关键词
医用光学
血液动力学
非随意注意
近红外脑功能成像
事件相关脑电位检测技术
medical optics and biotechnology
hemodynamics
nonselective attention
functional near-infrared imaging
event-related potential
