摘要
目的：探讨黄芪注射液治疗脑梗塞的疗效及其作用机制。方法：８０例经头颅ＣＴ检查证实的急性脑梗塞患者，按顺序分为２组，均在发病４８小时内应用药物治疗。治疗组静滴黄芪注射液，对照组静滴维脑路通，比较２组疗效。结果：治疗组和对照组总有效率分别为９２．５％与９０．０％，差异无显著性（Ｐ＞０．０５），而治疗组在２４小时内用药者疗效优于对照组，其神经功能缺损平均减少分数分别为（１１．７８±３．０８）分和（８．９６±２．８８）分，差异有显著性（Ｐ＜０．０５）；同时治疗组血液流变学指标与对照组比较均有显著性差异（Ｐ均＜０．０５）。结论：黄芪注射液与维脑路通临床疗效相近，但早期用黄芪注射液治疗者疗效优于维脑路通治疗者。
Objective:To explore the curative effect and mechanism of astragalus membranaceus injection in treating cerebral infarction.Methods:Eighty cases who had been confirmed the acute cerebral infarction diagnosis with CT examination.Forty cases were treated with astragalus membranaceus injection intravenous drip (treatment group) and compared with 40 cases (control group),who were treated with venoruton intravenous drip.The drugs were given within 48 hours at the onset.Results:The total effective rate was 92 5% in the treatment group and 90 0% in the control group respectively.There was no obvious difference between the two groups( P >0 05),while further analysis showed that the mean decreased scores of neurologic deficit(MDSND) was (11 78±3 08) scores in the treatment group and superior to control group (8 96±2 88) scores , P <0 05.In addition,there were obvious differences of hemorrheologic parameters between the two groups (all P <0 05).Conclusions:It indicates that the clinical curative effect of astragalus membranaceus is similar to venoruton,but the early curative effect and hemorrheologic change of astragali injection are superior to venoruton.
关键词
黄芪注射液
脑梗塞
急性
维脑路通
astragalus membranaceus injection\ \ acute cerebral infarction\ \ venoruton\ \ hemorrheology
