摘要
目的:了解TPO-Ab、TGA含量与不同类型自身免疫性甲状腺疾病的动态关系。方法:按临床诊断分成三组用罗氏电化学发光仪2010及配套试剂测定TPO-Ab、TGA的含量。结果:治疗前Graves组;桥本甲状腺炎组;原发甲减组与正常对照组的TPO-Ab、TGA含量有显著性差异(P<0.01),Graves组与桥本甲状腺炎组及原发甲减组的TPO-Ab、TGA含量又有显著差异(P<0.01),桥本甲状腺炎与原发甲减组则无差异(P>0.05)。治疗后虽含量明显下降,但桥本甲状腺炎组;原发甲减组的TPO-Ab、TGA含量与正常对照组仍有明显差异(p<0.01),而Graves组的TGAb、TPO-Ab含量与正常对照组无差异(P>0.05)。结论:测定TPO-Ab、TGA的含量在诊断、治疗及愈后方面都十分重要,需长期地,动态地观察。
Objective： To understand the dynamic relationship between the content of TPO- Ab, TGA and different kinds of self - immune thyroiditis. Method： Divide diseases into three groups according to the complete set of reagent to determine the content of TPO - Ab, TGA. Result： Before treatment , the content of TPO- Ab,TGA in the Graves group ;Hashimoto Throiditis group ;Primary Hypothyroidism group are obvi- ously different from the normal group which is used to compare （ P 〈0.01 ） , the content of TPO - Ab ,TGA in Graves group is remarkably different from the other two groups as well （ P 〈 0.01 ）, but there is no diversi- ty between Hashimoto Thyroiditis group and Primary Hypothroidism group （ P 〉 0.05 ） . Although the content drops notably after treatment, there is still markedly difference between Hashimoto Thyroidltis group ;Primary Hypothyroidism group and the normal group which is used to compare （ P 〈 0.01 ） , however the content of TPO - Ab ,TGA in Graves group is identical with the normal group（ P 〉0.05 ） . Conclusion： It＇ s very important for diagnosing treatment and the aspect of the diseases which are cured to determine the content of TPO -Ab ,TGA , it will take us a longterm to observe it and we should survey it dynamic.
出处
《河北医学》
CAS
2007年第10期1185-1187,共3页
Hebei Medicine
