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雄激素补充治疗男性慢性心力衰竭 被引量:1

Supplementary Androgen Therapy for Chronic Heart Failure in Men
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摘要 男性慢性心力衰竭患者的雄激素水平较正常人明显降低,生理剂量的雄激素补充治疗可以保护心脏的收缩功能、舒张血管、增加运动耐量、抑制炎症细胞因子激活以及改善神经内分泌的紊乱,是一种有效的辅助治疗方法。 Low plasma concentrations of androgen have been described in men with chronic heart failure, there are indications that physiological androgen treatment may protect cardiac systolic function, have vasodilating action, enhance exercise capacity, regulate pathological levels of inflammatory eytokines and neuro-endocrinal hormone. Physiological androgen treatment is available.
作者 韩颖 富路
出处 《心血管病学进展》 CAS 2007年第6期888-891,共4页 Advances in Cardiovascular Diseases
关键词 心力衰竭 雄激素 男性 heart failure androgen men
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  • 1Anker SD,Chua TP,Ponikowski P,et al. Hormonal changes and catabolic/anabolic imbalance in chronic heart failure and their importance for cardiac cachexia [J]. Circulation,1997,96(2) : 526-534.
  • 2Kontoleon PE, Anastasiou-Nana MI, Papapetuou PD, et al. Hormonal profile in patients with congestive heart failure [ J ]. Int J Cardiol, 2003,87 ( 2-3 ) : 179- 183.
  • 3Noirhomme P, Jaquet L, Underwood M,et al. The effect of chronic mechanical circulatory support on neuroendocrine activation in patients with end-stage heart failure [ J ]. Eur J Cardiothorac Surg, 1999,16 ( 1 ) : 63 -67.
  • 4富路,韩颖,李元十,朱立群,戴颖楠,高倩萍,曹君娴,马丹.男性慢性心力衰竭患者血清睾酮、雌二醇水平与心功能的相关性[J].中华心血管病杂志,2006,34(12):1108-1110. 被引量:18
  • 5Peter Y, Alison K, Death J. Androgens and cardiovascular disease[ J ]. Endocrine Rev,2003,24 ( 3 ) : 313 -340.
  • 6Ikeda Y, Aihara K,Sato T,et al. Androgen receptor gene knockout male mice exhibit impaired cardiac growth and exacerbation of angiotensin Ⅱ -induced cardiac fibrosis[J]. J Biol Chem ,2005,280 (33) :29661-29666.
  • 7Scheuer J,Malhotra A,Schaible TF,et al. Effects of gonadectomy and hormonal replacement on rat hearts [ J ]. Circ Res, 1987,61 ( 1 ) : 12 - 19.
  • 8Golden KL, Marsh JD, Jiang Y, et al. Gonadectomy of adult male rats reduces contractility of isolated cardiac myocytes [ J ]. Am J Physiol Endocrinol Metab, 2003,285 (3) : E449-F453.
  • 9Golden KL, Marsh JD,Jiang Y,et al. Acute actions of testosterone on contractile function of isolated rat ventricular myocytes [ J ]. Eur J Endocrinol, 2005,152 ( 3 ) : 479-483.
  • 10Jose MV, Cristian I, Manuel E, et al. Testosterone induces an intracellular calcium increase by anongenomic mechanism in cultured rat cardiac myocytes[J]. Endocrinology ,2006,147 ( 3 ) : 1386-1395.

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