摘要
首先合成低分子量的聚丙烯酰胺，再用甲醛使其羟甲基化，最后羟甲基化聚丙烯酰胺和丙烯酰胺缩合得到可室温交联的聚丙烯酰胺。研究了反应物摩尔比、反应温度、反应时间和溶液pH值等因素对羟甲基化和缩舍反应的影响，确定了最佳反应条件。这种改性聚丙烯酰胺的水溶液和交联剂于室温可快速交联得到凝胶体。该工艺的优点是对微生物细胞无毒性，聚合（包埋）温度低，交联发生在侧链使抗水解性增强。
In this paper first a polyacrylamide with low molecular weight was synthesized, then the polyacrylamide was hydroxymethylated with formaldehyde, finally the hydroxymethylated polyacrylamide and acrylamide reacted to form the cross-linking at room temperature polyacrylamide. The effects of the mol-ratio of reactants, reaction temperature, reaction time and pH on hydroxymethylation and condensation reaction were researched; the best synthesis process was given. This modified polyacrylamide and cross-linking agent are able to form gelatin at room temperature. The merits of this process are there is no toxic to microbial cells, the temperature of polymerization （entrapment）is lower, the cross-linking is at side chain and the anti-hydrolyzation ability is strong.
出处
《功能材料》
EI
CAS
CSCD
北大核心
2007年第A05期1848-1850,共3页
Journal of Functional Materials
基金
辽宁省教育厅高等学校科学技术研究资助项目（05L343）
关键词
改性聚丙烯酰胺
羟甲基化
室温交联
微生物包埋
modified polyacrylamide
hydroxymethylation
cross-linking at room temperature
bio-immobilization
