期刊文献+

联合吸入布地奈德混悬液和特布他林雾化液治疗婴幼儿哮喘的疗效 被引量:28

Curative Effects of Budesonide Suspension Combined with Ubertaline Solution for Nebulization on Infantile Asthma
下载PDF
导出
摘要 目的探讨联合吸入布地奈德混悬液和特布他林雾化液治疗婴幼儿哮喘的疗效及安全性。方法对75例哮喘婴幼儿采用双盲对照随机抽样法,设单纯吸入特布他林雾化液(A组)及联合吸入布地奈德混悬液和特布他林雾化液(B组)、单纯吸入布地奈德混悬液(C组)3组分别进行治疗,每组25例。观察比较3组疗效及安全性。结果A组治愈16例,显效3例,无效6例,总有效率76%;B组治愈22例,显效2例,无效1例,总有效率96%;C组治愈14例,显效4例,无效7例,总有效率72%。A、B组总有效率比较有显著性差异(P<0.05);B、C组总有效率比较有显著性差异(P<0.05);A、C组总有效率比较差异无显著性(P>0.05)。结论联合吸入布地奈德混悬液和特布他林雾化液治疗婴幼儿哮喘疗效优于单纯吸入特布他林雾化液和单纯吸入布地奈德混悬液,不良反应少,安全性好。 Objective To study the clinic effects and safety of budesonide suspension combined with tubertaline solution for nebulization therapy on infantile asthma.Methods Seventy-five cases with asthma were divided into 3 groups randomly,double-blinded and controlled,each group having 25 cases.Group A inhaling tubertaline solution(bricanyl),while group B inhaling pulmicort respules combined with bricanyl,group C inhaling budesonide suspension(pulmicort respules)only.Results In group A,16 cases was cure,3 cases was markedly improved,6 cases was failure,the total efficacy rate was 76 percent.In group B,22 cases was cure,2 cases was markedly improved,1 case failed,the total efficacy rate was 96 percent.While in group C,14 cases was cure,4 cases was markedly improved,7 cases failed,the total efficacy rate was 72 percent.The difference of efficacy rate between group A and group B was significant(P〈0.05),the difference between group C and group B was also significant(P〈0.05),while the difference between group A and group C was not significant(P〉0.05).Conclusion Pulmicort respules combined with bricanyl for nebulising inhalation is effective and safety on infantile asthma and its effect is better than inhaling bude-sonide or tubertaline only.
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2007年第4期301-301,318,共2页 Journal of Applied Clinical Pediatrics
关键词 联合吸入 布地奈德混悬液 特布他林雾化液 哮喘 儿童 combination inhalation,budesonide,tubertaline,asthma,child
  • 相关文献

参考文献12

二级参考文献25

  • 1韩美芹.氧气驱动备劳特液加普米克令舒气雾吸入治疗小儿毛细支气管炎31例疗效观察[J].中国全科医学,2005,8(7):588-589. 被引量:14
  • 2中华人民共和国卫生部.小儿肺炎防治方案[J].中华儿科杂志,1987,25:47-47.
  • 3李明华 殷凯生 等.哮喘病学[M].北京:人民卫生出版社,1999.570.
  • 4Bames PJ, Adcock IM. Anti - inflammatory actions of sterods: molecular mechanism. TREND Pharmacol Sci, 1993,14:436 ~ 441.
  • 5Pedersen S, Hansen R. J Allergy. Clin lmmunol, 1995,95:29 ~ 33.
  • 6全国儿科哮喘协作组.儿童哮喘病诊断标准和治疗常规[J].中华儿科杂志,1998,36(12):747-750.
  • 7中华医学会儿科学会呼吸学组.儿童哮喘防治常规(试行)[J].哮喘杂志,2004,10(1):44-44.
  • 8Peters SP.Safety of inhaled corticosteroids in the treatment of persistent asthma[J].J Natl Med Assoc,2006,98(6):851-861.
  • 9Scicchitano R,Aalbers R,Ukena D,et al.Efficacy and safety of budesonide/formoterol single inhaler therapy versus a higher dose of budesonide in moderate to severe asthma[J].J Trauma,2004,56(4):850-862.
  • 10O'Byrne PM,Bisgaard H,Godard PP,et al.Budesonide/formoterol combination therapy as both maintenance and reliever medication in asthma[J].Am J Respir Crit Care Med,2005,172 (2):129 -136.

共引文献2718

同被引文献137

引证文献28

二级引证文献161

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部