摘要
目的建立补肾丸的质量控制方法。方法采用薄层色谱(TLC)法对方中主要药材黄柏、山茱萸、生甘草分别进行定性鉴别,采用高效液相色谱(HPLC)法测定盐酸小檗碱的含量。结果定性鉴别方法重现性好、专属性强,含量测定方法的平均回收率为99.90%,RSD为0.95%。结论质量控制方法简单、易行、精密度高、重现性好,能够有效地控制补肾丸的质量。
Objective To establish a ,nethod for the quality control of Bushen Pill. Methods The qualitative analysis of Cortex Phellodendri, Comus officinalis Sieb. et Zucc. Radix Glycyn＇hiszae in Bushen Pill were identified by TLC. The content of berberine hydrochloride was determinated by HPLC. Results The qualitative identification was specific and reproducible. The average recovery rate of quantitative analysis was 99.90% and relative standard deviation was 0.95%. Conclusion The precision and reproducibility of the method is good, The method can be used for the quality control of Bushen Pill.
出处
《中国药业》
CAS
2007年第23期16-17,共2页
China Pharmaceuticals
