摘要
目的:探讨血清脂蛋白(a)水平对稳定性心绞痛患者冠状动脉支架置入术后6个月心血管事件和再狭窄的预测价值。方法:术前测定800例稳定性心绞痛患者冠状动脉支架置入术患者基础的血清脂蛋白(a)水平,分为脂蛋白(a)<300mg/L和脂蛋白(a)≥300mg/L两组,随访术后6个月内心血管事件(心肌梗死和死亡)发生率和支架内再狭窄等情况。结果:术后6个月主要心血管不良事件脂蛋白(a)≥300mg/L组和脂蛋白(a)<300mg/L相比有增加趋势;术后6个月内支架内再狭窄发生率在脂蛋白(a)≥300mg/L与脂蛋白(a)<300mg/L组相比明显升高。结论:基础血清脂蛋白(a)水平是稳定性心绞痛患者冠状动脉支架置入术后6个月心血管主要不良事件和支架再狭窄发生率的一个重要预测指标。
Objective To investigate whether the cardiovascular events in 6 months after coronary stent implantation could be predicted by baseline levels of lipoprotein （a）. Methods The lipoprotein（a） in 800 patients with stable angina with coronary stent implantation were measured. According to the level of lipoprotein （a）,the patients were divided into two groups, lipoprotein （a）〈300 mg/L group and lipoprotein（a）≥300 mg/L group. The cardiovascular events and stent restenosis were carefully observed and recorded in 6 months after the procedures. Results The cardiovascular events were more in lipoprotein （a）≥300 mg/L than lipoprotein （a）〈300 mg/L group. The frequency of restenosis in stent was significantly higher in lipoprotein （a）〈300 mg/L than lipoprotein （a）≥300 mg/L group. Conclusion Lipoprotein （a） is one of independent risk factors for coronary heart disease. To some degree,preprocedural lipoprotein（a） level may be a predictor about the cardiovascular events and stent restenosis after 6 months of patients with stable angina undergoing coronary stent implantation.
出处
《实用诊断与治疗杂志》
2007年第12期916-918,共3页
Journal of Practical Diagnosis and Therapy
