期刊文献+

肾功能及血透对慢性肾脏疾病患者血清肿瘤标志物的影响 被引量:1

下载PDF
导出
摘要 根据内生肌酐清除率(Ccr)水平将92例未行血透的慢性肾脏疾病(CKD)患者分为A、B、C三组,将53例尿毒症患者(Ccr≤10 ml/min)分为血透组和非血透组。采用电化学发光免疫分析法测定各组患者的血清癌胚抗原(CEA)、甲胎蛋白(AFP)、糖蛋白抗原19-9(CA19-9)、糖蛋白抗原125(CA125)、糖蛋白抗原72-4(CA72-4),并进行比较。结果CKD患者A组(Ccr≤30 ml/min)CEA明显高于B组(30 ml/min<Ccr<60 ml/min)及C组(Ccr≥60 ml/min),C组CA19-9显著低于A、B组;非血透组和血透组CEA及CA19-9均显著高于轻度肾功能损伤的C组,血透组CA125明显高于非血透组和C组(Ρ均<0.05)。提示CKD严重肾功能降低患者血清CEA和CA19-9显著升高,维持血透可导致血清CA125明显升高。
出处 《山东医药》 CAS 北大核心 2007年第34期71-72,共2页 Shandong Medical Journal
  • 相关文献

参考文献3

  • 1张悦,叶志斌,吉俊.肿瘤标记物在原发性肾脏疾病患者中的血清学浓度改变[J].中国临床医学,2005,12(1):135-137. 被引量:10
  • 2Xiao WB, Liu YL. Elevation of serum and ascites cancer antigen 125 levels in patients with liver cirrhosis [ J ]. J Gastroenterol Hepatol, 2003, 18 (11): 1315-1316.
  • 3Grzegorzewska AE, Mlot M, Leande M, et al. Serum levels of cancer antigen 125 and intetleukin-15 in relation to the nutrition status of peritoneal dialysis patients[ J]. Adv Peritoneal Dial, 2004,20 : 185-189.

二级参考文献15

  • 1Sevinc A,Buyukberber S,Sari R,et al. Elevated serum CA-125levels in patients with nephrotic syndrome-induced ascites[J].Anticancer Res,2000,20(2B) :1201-1203.
  • 2Yamashita F, Suzuki T, Takeuchi K, et al. Case of minimal change nephrotic syndrome with high levels of CA 125 antigen [J]. Nippon Naika Gakkai Zasshi,1995,10;84(6) :951-953.
  • 3Akashi, Y,Inoh, M,Gamo N,et al. Dermatomyositis associated with embranous nephropathy in a 43-year-old female[J]. Am J Nephrol,2002,22(4) :385-387.
  • 4Miret C, Font J, Molina R, et al. Lack of correlation between tumor markers (CA 125 and SCC) and systemic lupus erythematosus activity[J]. Anticancer Res, 1998,18(2B): 1341-1344.
  • 5Arik N,Adam B,Akpolat T,et al. Serum tumour markers in renal failure[J]. Int Urol Nephrol,1996,28(4):601-603.
  • 6Menzin AW,Kobrin S,Pollak E,et al. The effect of renal func tion on serum levels of CA 125[J]. Gynecol Oncol,1995,58(3):375-377.
  • 7Xiao WB,Liu YL. Elevation of serum and ascites cancer antigen 125 levels in patients with liver cirrhosis[J]. J Gastroenterol Hepatol,2003,18(11) :1315-1316.
  • 8Mayo Clin Proc. Cancer antigen 125 in patients with chronic liver disease[J]. 2002,77 (6): 538 -541.
  • 9Mas MR,Comert B,Saglamkaya U,et al. CA-125;a new marker for diagnosis and follow-up of patients with tuberculous peritonitis[J]. Dig Liver Dis,2000,32(7) :595-597.
  • 10Docci D, Pistocchi E, Turci F, et al. Serum CA19-9 and CA50antigens in hemodialysis patients [J]. Chn Nephrol, 1987; 27(4): 179-181.

共引文献9

同被引文献5

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部