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0.5%盐酸左旋丁萘酮心安对青光眼治疗的临床观察

A clinical observation on 0.5% levobunolol in treatment of glaucoma
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摘要 观察了β-受体阻滞剂——0.5%盐酸左旋丁萘酮心安(levobunolol)滴眼液对开角性青光眼及高眼压症等滴药前后的临床效果。17例33只眼作1滴药8小时观察,其中9例18只眼作每日二次连续点药1周及4周的观察。结果表明滴药后3~6小时出现降压高峰,1滴药作用持续8小时以上,1周及4周连续点药能维持较低眼压状态。对血压及脉搏无明显影响。无全身和局部明显不良反应。对青光眼长期局部用药安全有效。 A single drop test of 0.5% levobunolol, a new beta adrenergic blocker, was performed on 17 patients 33 eyes with primary open angle glaucoma and ocular hypertension, of which 9 patients 18 eyes were adminstered twice daily for 1 week and 4 weeks consecutively. Observations showed that intraocular pressure(IOP) decreased significantly during 3~6 hours after instillation. A single drop could lower IOP for 8 hours and consecutive instillation for 1 week and 4 weeks could keep IOP in low level. No obvious ocular or systemic adverse reactions were observed.
作者 陈虹 邵慧
出处 《北京医学》 CAS 北大核心 1997年第4期206-208,共3页 Beijing Medical Journal
关键词 左旋丁萘酮心安 Β-受体阻滞剂 青光眼 滴眼液 Levobunolol Beta adrenergic blocker Glaucoma
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