摘要
目的考察康复新结肠定位滴丸在体内结肠的定位释放性能。方法用γ-射线闪烁照相法考察包衣滴丸在犬体内的定位释药部位与释药时间。结果包衣滴丸在犬的横结肠和降结肠崩解释药。结论康复新结肠定位包衣滴丸具有结肠定位的释药性能。
OBJECTIVE To investigate the colon - specific delivery of Kangfuxin colon - specific drop pill. METHODS The releasing site and time of the drug from the colon - specific coated drop pill in dogs were investigated by gamma scintigraphy using ^99Tc^m as the marker. RESULTS The coated drop pills were released in dogs＇ transverse colon and descending colon. CONCLUSION Kangfuxin colon - specific coated drop pills possess the colon - specific delivery characteristics.
出处
《华西药学杂志》
CAS
CSCD
北大核心
2007年第6期661-662,共2页
West China Journal of Pharmaceutical Sciences
基金
国家自然科学基金项目(批准号:30371780)
国家"十一五"科技支撑计划项目(No.2006BAI09B08-14)
