摘要
目的:探讨非酒精性脂肪肝(NAFLD)发病与患者空腹血糖(FBG)、胰岛素抵抗指数(IR)、体重指数(BM I)及血脂紊乱的关系。方法:56例NAFLD患者,年龄、性别相匹配的正常对照者56例,检测空腹血糖、空腹胰岛素水平及血脂,采用稳态模式评估法计算胰岛素抵抗指数,测量身高、体重,计算BM I及腰臀比。结果:NAFLD组与对照组之间空腹胰岛素、胰岛素抵抗指数、BM I及血脂紊乱比较有显著差异(P<0.05或0.01);多元逐步回归显示,胰岛素抵抗、腰臀比是影响肝脏脂肪含量主要的危险因素。结论:胰岛素抵抗、腰臀比是影响NAFLD的主要危险因素。
Objective： To investigate the relationship among homeostasis model assessment of insulin re- sistance （ HOMA - IR） , blood glucose, body mass index（BMI） , waist - to - hip ratio（WHR） and dyslipi- dema in patients with non alcoholic fatty liver disease （ NAFLD ）. Methods： 56 NAFLD patients and 56 matched normal control groups, the level of homeostasis model assessment of HOMA -IR, blood glucose, WHR were measured. Results： HOMA - IR index, BMI, WHR and dyslipidema showed significant differ-ence between NAFLD, and normal groups （ P 〈 0.05 or P 〈 0.01 ）. Multiple stepwise regression analysis showed that HOMA - IR and WHR were the independent risk factors affecting. Conclusion： HOMA - IR and WHR can be important risk factors of NAFLD.
出处
《河北医学》
CAS
2007年第4期479-481,共3页
Hebei Medicine
关键词
非酒精性脂肪肝
胰岛素抵抗指数
临床观察
Non alcoholic fatty liver disease, NAFLD
homeostasis model assessment of insulin re-sistance （HOMA - IR）
