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局部晚期胆管癌28例三维适形放射治疗(3DCRT)分析 被引量:4

3DCRT for 28 Patients with Locally Advanced Bile Duct Cancer
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摘要 目的 探讨3DCRT治疗胆管癌的疗效。方法 不能手术的胆管癌28例,10例胆管引流术后行3DCRT;单纯3DCRT18例,肿瘤PTV单次剂量2Gy,30~35次、6~7周完成,总剂量60~70Gy。结果 肿瘤病灶完全缓解(CR)16例(57.1%),部分缓解(PR)8例(28.6%),总有效率(CR+PR)为85.7%,1年生存率为60.7%。结论 3DCRT治疗胆管癌能有效控制肿瘤,近期疗效满意,远期疗效及反应需进一步观察。 Objective To explore the effect of 3DCRT on Bile Duct Cancer. Methods From January 2002 to August 2005,10 cases from 28 patients with bile duct cancer were treated with 3DCRT after internal or external biliary drainage. 18 patients were treated with 3DCRT alone. 3DCRT was given 2Gy per fraction,30 - 35 fractions over 6 - 7 weeks ,with a total dose of 60 - 70Gy. Results Of the 28 patients, 16 achieved CR, and 8 patients achieved PR, with a total response rate 85.7%. 1 - year survival rate was 60.7% ( 17/28 ). Conclusion 3DCRT is an effective approach in the treatment of bile duct cancer. Long - term survival rate and toxicities need further study.
出处 《实用癌症杂志》 2007年第2期175-176,182,共3页 The Practical Journal of Cancer
关键词 胆管癌 放射治疗 适形放射治疗 Bile duct cancer Radiotherapy Conformation radiotherapy
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  • 1张天泽 徐光伟.肿瘤学[M].天津:天津科学技术出版社,1997.1897-1874.
  • 2Hsing AW, Gao YT, Devesa SS, et al. Rising incidence of biliary tract cancers in Shanghai, China [J]. Int J Cancer,1998,75 : 368.
  • 3Cameron JL, Pitt HA, Zinner MJ et al. Management of proximal cholangiocarcinoma by surgical resection and radiotherapy[J]. Am J Surg,1990,159(1) :91.
  • 4Alden ME, Mohiuddin M. The impact of radiation dose in combined external beam and intraluminal Ir-192 brachytherapy for bile duct cancer[J]. Int J Radiat Oncol Biol Phys, 1994,28(4) : 945.
  • 5Gonzalez Gonzalez D, Gerard JP, Maners AW, et al. Results of radiation therapy in carcinoma of the proximal bile duct(Klatskin tumor) [J]. Semin Liver Dis, 1990, 10(2) : 131.
  • 6Dawson LA, McGinn CJ, Normolle D, et al. Escalated focal liver radiation and concurrent hepatic artery fluorodeoxyuridine for unresectable intrahepatic malignancies[J].J Clin Oncol,2000,18(11):2210.
  • 7Foo ML, Gunderson LL, Bender CE, et al. Extermal radiation therapy and transcatheter iridium in the treatment of extrahepatic bile duct carcinoma[J]. Int J Radiat Oncol Biol Phys,1997,39(4) :929.
  • 8Sudan D,DeRoover A,Chinnakotla S,et al. Radiochemotherapy and transplantation allow long-term survival for nonresectable hilar cholangiocarcinoma [J]. Am J Transplant,2002,2(8) :774.
  • 9Kitamura K, Shirato H, Shimizu S, et al. Registration accuracy and possible migration of internal fiducial goid marker implanted in prostate and liver treated with real-time tumor-tracking radiation therapy (RTRT). Radiother Oncol, 2002, 62:275-281.
  • 10Lillemoe KD,Cameron JL.Surgery for hilar cholangiocarcinoma:The John's Hopkins approach.J Hepatobiliary Pancreat Surg 2000;7:115-121.

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