摘要
以锌原卟啉(ZnPP)为功能单体,甲基丙烯酸为共功能单体合成了生物碱基———胞嘧啶的分子印迹聚合物.通过静态吸附紫外检测的方法,对印迹和非印迹聚合物与胞嘧啶及腺嘌呤、尿嘧啶、胸腺嘧啶的结合特性分别进行了对比,分子印迹聚合物(MIP)与非分子印迹聚合物(NMIP)对胞嘧啶的吸附率差值为20.8%,远远高于其他三种碱基,说明MIP对胞嘧啶具有分子识别能力,实现了对胞嘧啶的分子识别.
Zinc(Ⅱ ) -protoporphyrin (ZnPP) and methacrylic acid (MAA) were used as functional monomer to synthesize molecularly imprinted polymer (MIP) for the selective recognition of cytosine. By batch adsorption studies, the recognition of MIP for nucleobases was investigated. The result shows that the adsorption percentage difference between MIP and NMIP with C (cytosine) is 20.8 %, much larger than that of A (adenine), T (thymine), and U (uracil). The MIP taking cytosine as template has selective recognition for cytosine.
出处
《化学研究》
CAS
2007年第4期59-61,共3页
Chemical Research
基金
河南大学自然科学基础研究基金资助课题(06YBZR012)
关键词
分子印迹聚合物
卟啉
胞嘧啶
分子识别
功能单体
molecularly imprinted polymers
protoporphyrin
cytosine
molecularly recognition
functional monomer